OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
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Rapid publication: manuscripts are undertaken in 12 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period).
Frailty in Older Adults
Submission Deadline: June 15, 2020 (Open) Submit Now
Pilar Pérez-Ros, MSc, PhD
Nursing Faculty, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain
Research interests: Gerontology; rehabilitation; geriatric assessment; fall prevention; frail elderly; frailty; falls; healthy aging
About This Topic
The aging process is holistic and is linked to increased comorbidity as well as the risk of increased dependency, the number of geriatric syndromes and the loss of quality of life.
Understanding frailty syndrome, biological bases, risk factors and adverse effects could improve the implementation of prevention strategies for this group of older people. The prevalence of frailty among community-dwelling people aged 65 years or over ranges from 4-59.1% and from 19% to 75.6% among Long Term Care.
Why are there so many discrepancies in prevalence rates? What are the most sensitive criteria for each older population? What prevention strategies are the most appropriate? Is there any type of physical exercise that is most appropriate? Is the interdisciplinary approach the most appropriate?
The aim of this special issue is to present the results and conclusions different researchers have found.
Received: 31 May 2020; Published: 10 July 2020; doi: 10.21926/obm.geriatr.2003127
With life-expectancy rising globally, the prevalence of ageing, comorbidity and frailty is likely to increase especially in the low and middle income countries. The emergence of the new COVID-19 pandemic has been concentrated in this group of patients and has led to worse outcomes compared to younger and less comorbid populations. This group [...]
Association between Very Low Dietary Protein Intake and Subsequent Falls in Community-Dwelling Older Adults in the United States
by marika paul , mary beth arensberg , judy simon , satya jonnalagadda , suzette pereira , jamie partridge and joseph rosenthal
Received: 10 April 2020; Published: 22 May 2020; doi: 10.21926/obm.geriatr.2002120
Poor nutrition is linked to frailty and both poor nutrition and frailty are recognized risk factors for falls. This study examined the association between dietary protein intake and subsequent reported falls in community-dwelling older Americans with a history of falls. Other nutritional, functional, and sociodemographic-related variables [...]
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