OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 12 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period). 

Current Issue: 2022  Archive: 2021 2020 2019 2018 2017

Special Issue

Geriatric Cardiac Diseases

Submission Deadline: March 15, 2022 (Open) Submit Now

Guest Editor

Giuseppe Cocco, MD

Emeritus Professor, Emeritus Fellow of the European Society of Cardiology, Cardiology Office, Marktgasse 10a, CH-4310 Rheinfelden, Switzerland

E-Mail

Research Interests: Geriatric cardiology; old cardiac patients; heart failure; geriatric cardiac diseases; noninvasive cardiovascular diagnostics and cardiovascular therapeutics

About This Topic

The special issue entitled "Geriatric Cardiac Diseases" aims to cover the latest and outstanding developments in the field of geriatric cardiac disease, focusing on known-unknowns in the diagnosis and therapeutics of this increasingly frequent pathology. The issue presents the specific characteristics of the elderly cardiac patients, dealing with prevention, the therapy of arterial hypertension, of arrhythmias (especially atrial fibrillation), of coronary artery syndromes, of valve heart diseases, and of heart failure. We will welcome research articles, review articles, editorials, case reports, perspectives, etc. The editor hopes that readers of this issue of the "Geriatric Cardiac Diseases" will find it of interest.

Publication

Open Access Review

Complex Pathology of Cardiac Syncope in Old Patients

Received: 07 February 2022;  Published: 16 June 2022;  doi: 10.21926/obm.geriatr.2202200

Abstract

Syncope is characterized by a transient and rapid loss of consciousness for a short duration, with full spontaneous recovery within minutes. Syncope causes up to 2% of all emergency medical consultations. The incidence of syncope is similar in men and women, is higher in old patients (slightly higher in old women). The prevalence of syncope [...]
Open Access Original Research

Left Atrial Systolic Force in Hypertensive Patients with Left Ventricular Hypertrophy: A Predictor of Incident Atrial Fibrillation. The LIFE Study

Received: 20 December 2021;  Published: 09 March 2022;  doi: 10.21926/obm.geriatr.2201194

Abstract

It remains unknown whether left atrial systolic force (LASF), a measure of left atrial function, can be used as a predictor of new-onset atrial fibrillation (NOAF). Furthermore, the effect of the treatment with atenolol and losartan on LASF is unclear. A total of 758 patients without atrial fibrillation at baseline were enrolled [...]
Open Access Original Research

A Point System Table to Estimate the Risk of Cardiovascular Events in Patients with Hypertension and Left Ventricular Hypertrophy: The LIFE Study

Received: 30 December 2021;  Published: 24 February 2022;  doi: 10.21926/obm.geriatr.2201189

Abstract

We aimed to assess some readily available patient characteristics such as urinary albumin excretion as predictors of a primary composite event of myocardial infarction, cerebral stroke, and cardiovascular death among patients with hypertension and left ventricular hypertrophy, and develop risk algorithms for the outcomes. A [...]
Open Access Review

Diagnosis and Therapy of Atrial Fibrillation in Geriatric Patients

Received: 16 January 2021;  Published: 28 July 2021;  doi: 10.21926/obm.geriatr.2103178

Abstract

Atrial fibrillation is very common in most old patients who need an adapted therapy due to their comorbidities. Before initiating an antiarrhythmic therapy, possible adverse effects, especially iatrogenic proarrhythmia, and extracardiac side-effects, must be considered. In geriatric patients with atrial fibrillation, heart rate [...]
Open Access Editorial

Geriatric Cardiac Diseases

Received: 20 March 2020;  Published: 01 April 2020;  doi: 10.21926/obm.geriatr.2002112
Announcement
Newsletter

TOP