Efficacy and Safety of Andrographolide and Favipiravir Versus Favipiravir Monotherapy in Patients with Mild COVID-19 Infection: A Multicenter Randomized Controlled Trial
Abstract
(ISSN 2573-4393)
OBM Integrative and Complementary Medicine is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. It covers all evidence-based scientific studies on integrative, alternative and complementary approaches to improving health and wellness.
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There is no restriction on paper length, provided that the text is concise and comprehensive. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.
Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.9 weeks; Submission to Acceptance: 14.7 weeks; Acceptance to Publication: 8 days (1-2 days of FREE language polishing included)
Special Issue
Complementary, Traditional, and Integrative Medicine for COVID-19
Submission Deadline: December 31, 2021 (Closed) Submit Now
Guest Editors
Sok Cheon Pak, PhD
School of Biomedical Sciences, Charles Sturt University, Panorama Avenue, BATHURST NSW 2795, Australia
Interests: Honeybee venom; Evidence-based practice; Signaling pathway; Integrative therapeutics
Soo Liang Ooi
School of Biomedical Sciences, Charles Sturt University, Panorama Avenue, BATHURST NSW 2795, Australia
Interests: Complementary therapies; Nutrition; Naturopathy; Microbiome
About this topic
Dear Colleagues,
SARS-CoV-2 is spreading over the world with no country spared from its infections. COVID-19 is the disease caused by this novel coronavirus, and it has already claimed over 120,000 lives with close to 2 million confirmed cases as of 15 April 2020. Sadly, the numbers are still rising fast each day with no sign of slowing down. This pandemic is expected to last for months to come with much of the world living in lockdown.
There is currently no effective treatment for COVID-19, and the earliest possibility of having a vaccine is not until early 2021. The medical world is actively trying to repurpose existing drugs and therapies to treat this disease. Among them include anti-viral agents used to treat SARS (Lopinavir-ritonavir), an experimental drug for Ebola virus (Remdesivir), and old anti-malarial mediations (Chloroquine / Hydroxychloroquine). Many clinical trials are currently in progress to validate the effectiveness of different repurposed therapies. The hunt for a cure is on-going.
Complementary, traditional, and integrative medicine can play a vital role in supporting the treatment of COVID-19. For example, many herbs possess anti-viral, anti-inflammatory, and antioxidant properties that can be extremely helpful in treating viral infections. Nutritional interventions also play a critical role in preventing and controlling the disease, especially among older patients with comorbidities. Probiotics have been suggested to be a potential adjunct treatment as some patients with COVID-19 showed gut dysbiosis with decreased Lactobacillus and Bifidobacterium. Hence, it will be a significant loss if the repertoire of non-pharmacological therapies is overlooked in the search for remedies. Yet, the dominant medical journals rarely feature the use of complementary, traditional, and integrative medicine in their COVID-19 publications.
This special issue provides an open forum for researchers to share their research findings in the use of complementary, traditional, and integrative medicine for COVID-19. We welcome contributions in any form, including letter to the editor, original research, case report, and review. Results from human clinical trials are particularly welcome.
Dr. Sokcheon Pak
Mr. Soo Liang Ooi
Guest Editors
Keywords:
• COVID-19
• Novel coronavirus
• Herbs
• Nutrition
• Nutraceutical
Planned Paper:
Manuscript Submission Information
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Publication
Efficacy and Safety of Andrographolide and Favipiravir Versus Favipiravir Monotherapy in Patients with Mild COVID-19 Infection: A Multicenter Randomized Controlled Trialby
Thaninee Prasoppokakorn
,
Supachaya Sriphoosanaphan
,
Nutbordee Nalinthassanai
,
Thitaporn Roongrawee
,
Pongtorn Hanboonkunupakarn
,
Pisit Tangkijvanich
and
Rungsun Rerknimitr
Abstract Reports indicate that Andrographolide inhibits viral replication and reduces COVID-19 symptoms. This study aimed to determine Andrographolide's additional effect and safety in mild COVID-19 patients treated with favipiravir. A multicenter, open-labeled, randomized controlled trial was conducted from October 2021 to February 2022 [...] |
Kidney Transplantation during the COVID-19 Pandemic: From Past through Present Time of Emerging Vaccineby
Arksarapuk Jittirat
,
Natsuki Eguchi
,
Natthavat Tanphaichitr
,
Myreen Tomas
,
Praveen Gundelly
,
Kai Zhao
,
Leal Herlitz
,
Yasolatha Chalicheemala
,
Himabindu Yerneni
,
Rachel C. Forbes
,
Beatrice P. Concepcion
and
Ekamol Tantisattamo
Abstract The novel coronavirus disease 2019 (COVID-19) pandemic has significantly impacted kidney transplantation worldwide. The rate of kidney transplantation decreased during the peak of the COVID-19 pandemic, especially living donor kidney transplantation. Kidney transplant recipients are at high [...] |
Physical Activity Behaviors and COVID-19 SymptomsAbstract Statistical modeling indicated that COVID-19 would have afflicted more than 60% of the US population. Social distancing, self-quarantine, and widespread shutdowns were imposed. The push to stay at home and the decreased availability of exercise facilities have potentially reduced physical activity (PA) [...] |
The Effect of Chinese Medicine for Rehabilitation of Discharged COVID-19 Patients: A Protocol for Multi-Center Observational Studyby
Linda ZHONG
,
Yi-Ping Wong
,
Bo Peng
,
Zhi-Xiu Lin
,
Vivian Wong
,
Yi Luo
,
Hai-Yong Chen
,
Chao-Dong Chao
,
Chor-Fung Wong
,
Freddie Shung-Chi Tam
,
Kui Chan
,
Kwan-Yiu Lee
,
Lai-Fun Ho
,
Alan Yat-Lun Wong
,
Chi-Fung Choy
,
Bacon Fung-Leung Ng
,
Rowena How-Wan Wong
,
Yi-Bin Feng
,
Ching Liong
and
Zhao-Xiang Bian
Abstract The COVID-19 pandemic has lasted for more than 16 months, and there have been over 169 million confirmed cases worldwide. Besides, after treatment with Western medicine or undergoing home quarantine, COVID-19 patients are still severely or mildly functionally impaired. Though COVID-19 patients were discharged from the hospital [...] |
Traditional, Complementary and Integrative Medicine Approaches to COVID-19: A Narrative ReviewAbstract Traditional, complementary, and integrative medicine (TCIM) approaches to COVID-19 represent a paradigm shift from Western medicine, in that TCIM emphasizes prevention, encouraging wellness, and supporting health and recovery. A wide range of TCIM approaches exist: whole medical systems (such as traditional Chinese medicine), mind [...] |
Body-Mind Medicine Interventions in COVID-19 Place Confinement for Mental, Physical and Spiritual WellbeingAbstract The SARS-COV-2 virus has changed people’s lives and caused significant public health issues. The lockdown implemented by several governments across the globe has raised serious concerns on mental and physical wellbeing. Doctors, nurses and other COVID-19 frontline workers being put under extreme pressure to attend to patients [...] |
Impact of SARS-CoV-2 Outbreak on Physical and Mental Health, Psychological Distress, and Suicidal Ideation, and the Mediating Role of StressorsAbstract This study investigated the physical and psychological impacts of elements related to coronavirus disease (COVID-19) and demographic data in Japan both directly and as mediated by stressors, immediately following the rescinding of the state of emergency declaration accompanying the severe acute respiratory syndrome coronavirus 2 outbreak. [...] |
Mental Health Effects of COVID-19 Pandemic on Healthcare WorkersAbstract Healthcare workers (HCWs) have been adapting to the changing needs of people worldwide in response to the COVID-19 pandemic. The purpose of this descriptive study was to evaluate how HCWs are managing dietary self-care needs during the increased stress-load of the COVID-19 pandemic and determine if nutritional changes are being made that could [...] |
A Potential Role of Coenzyme Q10 Deficiency in Severe SARS-CoV2 InfectionAbstract There is a dramatic need for extensive research into the predictors of severe infection with SARS-CoV2 and therapeutic options for infected people. People who suffer from severe illness and higher mortality display a pattern of having specific co-morbidities (diabetes, obesity, hypertension) and are of higher age. Recent research has described [...] |
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