Prenatal and Preimplantation Genetic Diagnosis of Huntington's Disease
Abstract
(ISSN 2573-4407)
OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).
OBM Neurobiology publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.
Publication Speed (median values for papers published in 2023): Submission to First Decision: 7.5 weeks; Submission to Acceptance: 15.9 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)
Special Issue
Huntington's Disease Research
Submission Deadline: December 15, 2020 (Closed) Submit Now
About This Topic
Huntington's disease (HD), is caused by a mutation in the gene for a protein called huntingtin, which causes brain cells, called neurons, to die in various areas of the brain. The mutation of HD is present from birth, which mainly appear in children (juvenile HD) and middle age (adult HD). The disease gets progressively worse over time, attacks motor control regions of the brain, as well as other areas. Chorea, abnormal body postures, and impaired coordination are among the most visible symptoms. But HD also causes changes in emotion and cognition (thinking). Moreover, there is no treatment that can stop or reverse the course of HD that can be devastating for people with the disorder and for their families. In this special edition, we invite submissions that show case new, inventive and original approaches to longstanding issues in Huntington's disease assessment, treatment and research. Original research reports, review articles, communications, and perspectives are welcome in all areas pertinent to this topic. All accepted papers will be published free of charge.
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (neurobiology@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
Welcome your submission!
Publication
Prenatal and Preimplantation Genetic Diagnosis of Huntington's DiseaseAbstract Huntington’s disease (HD) is an autosomal dominant disease that immensely impacts the affected families. However, the transmission of the disease from carriers to their offspring could be prevented. Prenatal diagnosis (PND) and preimplantation genetic diagnosis (PGD) are the only two available reproductive options for the carriers at risk [...] |
2023 | ||
CiteScore | SJR | SNIP |
1.0 | 0.232 | 0.256 |
TOP