OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).

OBM Neurobiology publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.

Publication Speed (median values for papers published in 2023): Submission to First Decision: 7.5 weeks; Submission to Acceptance: 15.9 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)

Current Issue: 2024  Archive: 2023 2022 2021 2020 2019 2018 2017

Special Issue

Neuroprotection, Neuroregeneration and Neuroplasticity

Submission Deadline: June 30, 2022 (Open) Submit Now

Guest Editor

Ping K. Yip, PhD

Lecturer, Center of Neuroscience, Surgery and Trauma, Blizard Institute, Barts and London School of Medicine and Dentistry, Queen Mary University of London, UK

Website1 | Website2 | E-Mail

Research Interests: Spinal Cord Injury; Traumatic Brain Injury; Hypoxic-Ischemic Encephalopathy; Peripheral Nerve Injury; Neuroregeneration; Neuroplasticity; Neuroprotection; Neuroinflammation

About This Topic

Injury to the central nervous system (CNS) such as by trauma and/or ischemia can result in death or long term disability. To date, there are no effective therapies to treat paralysis of limbs or loss of bodily functions involving organs such as the eye or bowel. Furthermore, patients can experience debilitating pain that can not be managed effectively. Therefore, there is an urgent clinically unmet need to improve the lives of CNS-injured patients. One particular direction of research is to protect neurons from cell death or induce axonal regeneration in damaged neurons and/or induce collateral sprouting in uninjured neurons. In this special edition we invite submissions that specifically focus on novel, inventive and original approaches to encourage neuroprotection, neuroregeneration and/or neuroplasticity in post-CNS injury. Our aim is to highlight targeting neurons can be beneficial to treating CNS injury after the injury has occurred.

Planned Papers

Title: Mortality in older patients with mild traumatic brain injuries
Authors: Mª Angustias Ibañez Perez de la Blanca
Affiliation: Emergency Unit, Hospital virgen de las Nieves, Granada, Spain.

Title: Neuroplasticity, Central Sensitization in Orofacial Pain and TMD
Author:  Helena M. Minye
Affiliation: Center for Reconstructive Dentistry & Oral Surgery, P.C

Title: Synaptic plasticity and learning processes: the neuropedagogic perspective
Author: Debora Di Jorio
Affiliation: OIDA Centro Psicopedagogico Formazione Studi e Ricerche, Napoli, Italy

Manuscript Submission Information

Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (neurobiology@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.

Welcome your submission!


Open Access Original Research

The Impact of Physical Activity on Brain Neuroplasticity, Cognitive Functions and Motor Skills

Received: 20 December 2023;  Published: 25 April 2024;  doi: 10.21926/obm.neurobiol.2402219


The research aims to study the mechanisms and factors contributing to brain neuroplasticity. To achieve this goal, the following methods were used: analysis and synthesis, hermeneutic method, psychological testing, and comparative and generalization methods. The research results revealed the nature of the concept of brain neuroplasticity and [...]
Open Access Review

Neuroprotective Potentials of Honey for Cerebral Small Vessel Disease

Received: 31 July 2022;  Published: 14 November 2022;  doi: 10.21926/obm.neurobiol.2204144


The nectar produced by bees in nature is known as honey and has been consumed for its nutritional and medicinal properties. There is growing evidence that honey and its compounds have anti-inflammatory, antioxidant and anti-microbial properties that are relevant to the maintenance of health and the prevention of illnesses, including cardiocere [...]
Open Access Research Article

Neuroprotective (Antioxidant, Antiamyloidogenic, and Antiexcitatory) Effects of TrévoTM against Cadmium Chloride Neurotoxicity in Adult Male Wistar Rats

Received: 29 May 2022;  Published: 26 September 2022;  doi: 10.21926/obm.neurobiol.2203135


Cadmium (Cd) is a heavy metal that is deleterious to brain development as it increases brain aging. Trévo is a multi-herbal supplement that provides various health benefits, including boosting the immune system and detoxification. In this study, we investigated the neuroprotective effects of Trévo against the neurotoxic effects of cadmium [...]
Open Access Commentary

Targeting Neuroplasticity for the Management of Pain and Agitation in Alzheimer’s Disease via Bergamot Nanotherapy

Received: 05 July 2022;  Published: 14 September 2022;  doi: 10.21926/obm.neurobiol.2203133


Alzheimer’s disease (AD) accounts for 50–70% of cases of dementia worldwide and is a social burden to the affected population. Although several pathogenetic hypotheses have been proposed, evidence favoring the role of aberrant neuroplasticity in the development of the neuropsychiatric symptoms associated with dementia is increasing. Specif [...]
Open Access Review

The Therapeutic Potential of the Stem Cell Secretome for Spinal Cord Repair: A Systematic Review and Meta-Analysis

Received: 26 October 2020;  Published: 14 December 2020;  doi: 10.21926/obm.neurobiol.2004080


There is currently no effective treatment for spinal cord injury leaving around 90% of patients with permanent disabilities. Stem cell therapies are showing promise in preclinical studies of central nervous system injury and there is increasing evidence suggesting the improvements in functional recovery are mediated by paracrine actions. In [...]
Open Access Review

Palmitoylethanolamide for Neurological Disorders

Received: 04 October 2020;  Published: 30 December 2020;  doi: 10.21926/obm.neurobiol.2004076


Neurological tissue along with the cartilage remains one of the tissues that escapes human efforts of regeneration after injury. The human body, after an injury, can repair its tissues only to a certain extent that can help in recovering the function of organs. However, this is not the case in some organs, such as the brain and spinal cord [...]
Open Access Review

Peripheral Nerve Dysfunction after Spinal Cord Injury

Received: 02 October 2020;  Published: 29 December 2020;  doi: 10.21926/obm.neurobiol.2004075


Spinal cord injury (SCI) leads to an immediate loss of sensory and motor function below the level of injury mostly affecting people in the prime of life. In addition to the primary injury there is accumulating neurophysiological and histological evidence of dysfunction in the peripheral nerves, not related to direct damage from the primar [...]
Open Access Review

Synaptic Plasticity and Learning Processes: A Neuroeducation Perspective

Received: 14 April 2020;  Published: 22 June 2020;  doi: 10.21926/obm.neurobiol.2002063


The story of each individual is essentially the story of theirlearning processes and relationships from the moment they were born. Indeed, the story of learning processes is merely a constant stratification of experiences based on biological and neurofunctional features that are influenced by genetic and cultural factors and subject to environ [...]
Open Access Review

Neuroprotective Strategies in Glaucoma - Translation to Clinical Trials

Received: 16 April 2020;  Published: 15 June 2020;  doi: 10.21926/obm.neurobiol.2002062


Neuroprotection in glaucoma is any medical treatment by which decline in visual function can be slowed or prevented by supporting the health and survival of neural cells, independent of lowering of intraocular pressure (IOP). This is achieved by targeting mechanisms to inhibit or delay retinal ganglion cell death and promote cell survival [...]
Open Access Review

Neuroplasticity and Central Sensitization in Orofacial Pain and TMD

Received: 06 February 2020;  Published: 18 May 2020;  doi: 10.21926/obm.neurobiol.2002057


Temporomandibular disorders (TMD) are a group of musculoskeletal and neuromuscular conditions that involve the temporomandibular joint (TMJ), the masticatory muscles, and branches of the trigeminal nerve. TMD is the most common chronic oral facial pain disorder. Pain associated with TMD can be clinically expressed as myogenous or arthrogenous [...]