Special Issue

Challenges and Future Trends of Transplant Immunology

Submission Deadline: July 31, 2026 (Open) Submit Now

Guest Editor

Malgorzata Kloc, PhD, Dr. Sc.

1: Weill Cornell Professor of Cell and Molecular Biology, The Methodist Hospital Research Institute, Houston, TX, USA

2: Adjunct Professor, M. D. Anderson Cancer Center, University of Texas, Houston, TX, USA

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Research Interests: Role of structural RNA in the organization of cellular cytoskeleton; Germ cells, development, germ cell fate; Role of macrophages; actin cytoskeleton and RhoA pathway in chronic rejection of transplanted organs; Mechanotransduction effects on actin cytoskeleton, RhoA pathway, and macrophages

About This Topic

Since the first successful kidney transplantation from one identical twin to the other in 1954 and the development of the first effective immunosuppression protocols applying azathioprine and corticosteroids, followed by the development of calcineurin inhibitors and antibody therapies, the field of transplant immunology has undergone constant advancement in therapeutic approaches and our understanding of molecular and cellular mechanisms triggering organ rejection and acceptance, allowing long term survival and functioning of genetically mismatched grafts. The progress in understanding how the T cells, B cells, macrophages, natural killer (NK) cells, and dendritic cells respond to organ transplantation and the role of immune memory in this process will allow the development of novel immune therapies. Additionally, transplant immunology embraces novel ideas and techniques, such as stem cell transplantation approaches, when stem cells are introduced into a patient to regenerate a damaged organ, and modern technologies, including artificial intelligence, gene editing of donor organs, and nanotechnology for targeted drug delivery, immunomodulation, mitigation of ischemia-reperfusion injury, and real-time monitoring of graft functions. In this special issue, we invite original research and review papers on all these subjects and beyond.

Keywords

Transplant immunology; organ rejection; immune memory; stem cell transplantation; organ gene editing; immunomodulation; immune cells; transplant therapies

Manuscript Submission Information

Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (transplantation@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.

Welcome your submission!

Publication

Open Access Research Article Short-Term Impact of Hematopoietic Stem Cell Transplantation in Leukemia Patients on Bone Bio Markers, Electrolytes and Blood Profile by Rhythm Joshi  , Zehva Khan  , Aakriti Garg  , Nidhi  , Ubada Aqeel  , Dinesh Bhurani  and Mohd.Ashif Khan Received: 30 September 2022;  Published: 25 April 2023;  doi: 10.21926/obm.transplant.2302183 Abstract Hematopoietic stem cell transplantation (HSCT) or Bone Marrow Transplantation (BMT) has significantly improved the survival rates of patients suffering from hematological malignancies. However, the cure can only be achieved at the price of morbidity and long-term complications such as bone diseases leading to fractures and osteopen [...]