OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
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We welcome original clinical studies as well as basic science, reviews, short reports/rapid communications, case reports, opinions, technical notes, book reviews as well as letters to the editor.
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Research on Xenotransplantation
Submission Deadline: November 30, 2021 (Open) Submit Now
Suzanne Bertera, PhD
Institute of Cellular Therapeutics, Allegheny-Singer Research Institute, Allegheny Health Network, South Tower, 320 East North Avenue, Pittsburgh, PA 15212-4772, USA
Research Interests: Diabetes research; islet isolation and transplantation; islet xenotransplantation; cell transplantation; gene therapy
About This Topic
This special issue focuses on xenotransplantation of tissues, cells, and organs. Xenotransplantation is widely seen as one of the options available to narrow the gap between human organ donors and demand for organs for transplantation. Advancements in understanding the mechanisms of xeno-rejection, improved immunosuppressive options, and easier methods of genetic manipulation of potential pig organ donors have helped bring xenotransplantation from the realm of science fiction to the dawn of a clinical age. Pig tissues such as heart valves are already transplanted into patients, clinical trials of porcine corneas and islet cells have been undertaken, and preliminary data suggests the first clinical trials of kidney and heart may soon begin. Authors are invited to submit reviews and commentaries or original data for peer review. This issue is intended as a single source to provide up to date knowledge and opinion on xenotransplantation. Topics may include the advantages and limitations of using various animal models, preliminary data on organ or cellular cross-species transplantation, immunology, methods of animal cloning or genetic manipulation, public opinion and ethics of xenotransplantation, or any topic relevant to the field.
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