Assessment of the Processing Method for the Development of Hybrid Biopolymer-Based Scaffolds
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Abstract
1253 7762
Assessment of the Processing Method for the Development of Hybrid Biopolymer-Based Scaffoldsby
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The present study deals with the development of scaffolds based on gelatin (G) and/or chitosan (CH) through modifications in the central processing method. This process consists of the fabrication of a hydrogel which is, then submitted to a freeze-drying stage. To compare the effects of the different modifications, the mechanical properties of the various systems were characterized, employing both dynamic compressive strain and frequency sweep tests. In addition, their porosity as well as the structure and fiber di [...] 1253 7762 |
Initial Adhesion Behavior of Osteoblast on Titanium with Sub-Micron Scale Roughnessby
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The surface roughness of titanium could regulate various cellular functions such as survival and growth. In the context of cell adhesion to materials, cell spreading and cell shape are also closely linked to various cellular functions. Previously, we found that Ti substrate with a 100-nm scale surface roughness reduced cell survival. However, effects of surface roughness on cell shape were not investigated. Herein, we quantified the initial adhesion behavior of osteoblasts on a Ti substrate with ~100 nm scale surfa [...] 1629 10227 |
Relativistic Wigner Function for Quantum WalksAbstract
A relativistic Wigner function for free Discrete Time Quantum Walks (DTQWs) on the square 2D space-time lattice is defined. The transport equation obeyed by the relativistic Wigner function is derived in terms of discrete derivatives and degenerates in the continuum limit into the transport equation obeyed by the Wigner function of 2D Dirac fermions. The first corrections to the continuous equation induced by the discreteness of the lattice are also determined and the similarities with non-quantum relativistic tran [...] 1254 7720 |
Phase Equilibria of Flexible Polymer and Monomer Liquid Crystal Blendsby
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In this study, we explored the phase equilibria in blends of a nematic liquid crystal monomer and a nematic liquid crystal flexible polymer within the whole composition of the phase diagram. The crystal-nematic and nematic-isotropic transition temperatures, as well as the transition enthalpies and entropies, indicated the total miscibility in this mesogenic blend system. We also extracted an empirical axial ratio of 4.52 for the polymer from the nematic-isotropic transitions of the blends. Further, from the biphasi [...] 1143 7754 |
Mesoporous Silica Nanoparticles to Tune Oxidative Degradation Rates in Composite Shape Memory PolymersAbstract
Biomedical applications of shape memory polymers (SMPs) are limited by their biostability, degradability, and possible toxicity risks after implantation. Mesoporous silica nanoparticles (MSNs) were used to increase the oxidative biostability (increase time until degradation occurs) using antioxidants and to induce oxidative degradation through incorporation of hydrogen peroxide-containing MSNs with modified surfaces. The presented results confirm increased oxidative stability using antioxidants, and alternatively, [...] 1245 8002 |
Silk-CNT Mediated Fibroblast Stimulation toward Chronic Wound RepairAbstract
Background: Diabetic patients suffer from chronic wounds partly due to altered function of fibroblasts. Fibroblasts of diabetic patients synthesize collagen I (COLI) at a much higher level than collagen III (COLIII), resulting in delayed tissue granulation and, consequently, a delay in the overall wound healing process.
Methods: We aimed to revive the matrix protein productivity of diabetic fibroblasts by employing aligned, electrically conductive and biocompatible spider silk-CNT fibers as a cell culture matrix t [...] 1607 9859 |
Engineering Bacterial Cellulose for Diverse Biomedical ApplicationsAbstract
Increasing interest in bacterial cellulose due to the huge potential which exists for the development of this new biomaterial for medical applications has been met with recent growth in research in engineering this unique microbial manufactured material. The mechanical properties, porosity, and biocompatibility of bacterial cellulose derived biomaterials are particularly attractive for use in wound healing, tissue engineering, and drug delivery applications. Advances in synthetic biology and soft materials engineer [...] 1782 13614 |
Electrochemical Atomic Layer Epitaxy Deposition of Ultrathin SnTe Filmsby
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Tin telluride (SnTe) ultrathin films were deposited electrochemically on polycrystalline and monocrystalline gold substrates using the electrochemical atomic layer epitaxy (ECALE) method. The electrochemical behaviors of Sn and Te were studied systematically by means of cyclic voltammetry. Cyclic voltammetry curves for Sn displayed a broad peak in the region between -0.15 V and -0.35 V, which was related to the under-potential deposition (UPD), while the curves for Te displayed a peak at 0.3 V for Te UPD. X-ray pho [...] 1311 87007 |
Formulation-Properties of Novel Ibuprofen-Loaded Soy Protein Wound DressingsAbstract
Background: Wound management is an important field in medical care, as annually, millions of wounds require treatment worldwide. Soy protein is highly biocompatible, easily processed, and a relatively cheap natural polymer, which can be used for wound dressing applications.
Methods: In this study, solvent cast soy protein films, plasticized by glycerol and cross-linked by glyoxal, were thermally treated and their mechanical properties were evaluated as a function of various processing parameters. Samples were then [...] 1477 7182 |
Super-Resolution of Nano-Materials and Quantum Effects Obtained by Microspheresby
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Microsphere super-resolutions, which are beyond the Abbe classical limit, are described. The conversion of evanescent waves to propagating waves, are analyzed by using the geometry of the microsphere. In microsphere experiments a nanojet is produced near the focal plane where its width is smaller than the Abbe limit and this width remains unchanged in the axial direction for some wavelengths. The interference between evanescent waves converted to propagating waves and the nanojet leads to increase in light intensit [...] 1279 7410 |
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