Table of Content

Open Access Review

Ketogenic Therapy for Major Depressive Disorder: A Review of Neurobiological Evidence

Received: 06 December 2021;  Published: 17 February 2022;  doi: 10.21926/rpn.2201003

Abstract

Major depressive disorder (MDD) is a debilitating illness that places a great burden on global health. A ketogenic diet, which has traditionally been used for treating refractory epileptic disorders, is being increasingly explored for its potential of alleviating other neuropsychiatric conditions. Providing an up-to-date summary on the ketogenic diet’s potential to alleviate MDD, its neurobiological basis, and preliminary clinical evidence. A structured literature survey was performed, and a narrative review was wr [...]

1293 19811

Open Access Review

Parenteral Nutrition: Review of Recent American Society for Parenteral and Enteral Nutrition Publications

Received: 30 December 2021;  Published: 15 February 2022;  doi: 10.21926/rpn.2201002

Abstract

Parenteral nutrition (PN) is a complex medication administered to adult, pediatric, and neonatal patients. PN is recognized as a high-alert medication by the Institute for Safe Medication Practices (ISMP). The American Society for Parenteral and Enteral Nutrition (ASPEN) has published several key recommendations regarding safe use of PN. This manuscript will review several of the important PN papers published in 2020-2021 by ASPEN.

1427 9059

Open Access Research Article

An Exploration of Preschool Teachers’ Perceptions of Physical Activity Integration in a Whole Child Pilot Curriculum

Received: 15 November 2021;  Published: 13 January 2022;  doi: 10.21926/rpn.2201001

Abstract

It is recommended that children ages 3-5 receive 180 minutes of physical activity a day, with at least 60 minutes of moderate-to-vigorous physical activity. Despite these recommendations, a majority of preschoolers are not provided opportunities in the early childhood education setting to meet these daily recommendations through either structured or unstructured physical activity. Accordingly, the number of young children identified as overweight or obese over the past couple of decades has increased. Critical to a [...]

1453 9630

Open Access Original Research

Consumption of a Recommended Serving of Wheat Bran Cereals Significantly Increases Human Faecal Butyrate Levels in Healthy Volunteers and Reduces Markers of Inflammation Ex Vivo

Received: 08 October 2021;  Published: 17 December 2021;  doi: 10.21926/rpn.2104002

Abstract

Wheat bran cereals are an important source of dietary fibre. The aim of the study was to investigate if a high intake (120 g) of fibre rich breakfast cereal (which delivers the UK Government guidelines for fibre intake in one serving but is three-fold higher than the manufacturers recommended serving) has additional potential health benefits compared to the recommended serving (40 g, containing 11 g of dietary fibre). To assess this, the study determined the short chain fatty acid (SCFA) profiles in human faecal, u [...]

1514 11474

Open Access Original Research

Ad Libitum Western Diet Feeding Does Not Alter Basal Skeletal Muscle Heat Shock Protein Expression in Sedentary or Aerobically Trained Young Rats

Received: 03 August 2021;  Published: 15 October 2021;  doi: 10.21926/rpn.2104001

Abstract

Poor dietary habits can lead to obesity and insulin resistance—both of which can impair basal heat shock protein (HSP) expression and the HSP stress response in skeletal muscle. It remains unclear if impairments in HSP expression occur during the early stages of diet-induced obesity and metabolic dysfunction. We determined if basal HSP expression (HSP70, HSP60, HSP25) was impaired in sedentary or exercised rats following the onset of diet-induced obesity. Male Long-Evans rats (N=6-7/group) were assigned to a Wester [...]

1075 8411