by Steven R. Brenner

Received: 29 August 2018;  Published: 26 February 2019;  doi: 10.21926/obm.geriatr.1901035

Alzheimer Disease may result from excessive stimulation of the innate immune system from development of underlying opportunistic infections and impaired age related self recognition as non-self, due to immunodeficiency and immunosenescence, resulting in excessive inflammation and runaway Beta-amyloi [...]

by Michael Fossel

Received: 31 December 2018;  Published: 15 February 2019;  doi: 10.21926/obm.geriatr.1901034

The consensus that cell senescence plays a role in age-related disease has prompted a number of potential clinical interventions, including attempts to reset cell senescence and attempts to remove senescent cells from aging tissues. The latter approach, senolytic therapy, has attracted considerable [...]

by Marco Barale  , Ruth Rossetto Giaccherino  , Ezio Ghigo  and Massimo Procopio

Received: 31 October 2018;  Published: 14 February 2019;  doi: 10.21926/obm.geriatr.1901033

Background: It is well known that hypovitaminosis D has been associated with various cardio-metabolic disorders, though the pathogenetic link, if any, still remains unclear. The aim of our pilot study was to evaluate in uncontrolled non-insulin-treated type 2 diabetic patients with hypovitaminosis D [...]

by Rachel Mills  , Louisa Jackman  , Mithila Mahesh  and Ian James

Received: 12 December 2018;  Published: 11 February 2019;  doi: 10.21926/obm.geriatr.1901032

Background: Research suggests that the use of lies and deception is prevalent within dementia care settings, despite ongoing debates raised about the ethics of this approach. There has been increasing exploration of when and why deceptive practices should be used, but the lack of clarity as to what [...]

by Michael Fossel

Received: 29 January 2019;  Published: 30 January 2019;  doi: 10.21926/obm.geriatr.1901031

Telomere Editorial-Perspectives on Telomeres and Aging

by Anya Ahmed  , Paula Ormandy  and Maaike L. Seekles

Received: 15 November 2018;  Published: 24 January 2019;  doi: 10.21926/obm.geriatr.1901030

Promoting a good quality of life for the oldest members of society has become a top priority as evidenced in UK policy. The ‘household’ model is a departure from traditional approaches to care provision since it offers person-centred support - combing health and social care - to older people in spec [...]

by Elizabeth Orsega-Smith  , Stephen Goodwin  , Melissa Ziegler  , Katie Greenawalt  , Jennie Turner  and Erica Rathie

Received: 31 October 2018;  Published: 10 January 2019;  doi: 10.21926/obm.geriatr.1901029

Background: Research has shown that positive psychology interventions can enhance subjective well-being and reduce depression, however, the efficacy of these programs with older adult populations has not been widely examined. The present study studied the short and long term impact of an interventio [...]

by Filomena Papa  , Bartolomeo Sapio  and Enrico Nicolò

Received: 31 October 2018;  Published: 04 January 2019;  doi: 10.21926/obm.geriatr.1901028

Background: Information and Communication Technologies (ICTs) could have a lot of potentialities to promote healthy aging and to increase the quality of life of elderly people. Several barriers like access, performance, psychological, and privacy issues still exist against fully deploying ICT soluti [...]

by Feliciano Villar  , Montserrat Celdrán  , Rodrigo Serrat  and Valentina Cannella

Received: 07 November 2018;  Published: 26 December 2018;  doi: 10.21926/obm.geriatr.1804027

Active aging is a concept used to describe and promote lifestyles that contribute to successful aging. However, these lifestyles vary widely, and the concept of active aging encompasses many activities. This paper considers two axes to classify the range of activities that can contribute to active a [...]

by Robert Zheng

Received: 05 October 2018;  Published: 25 December 2018;  doi: 10.21926/obm.geriatr.1804026

The current article addresses the working memory constraints experienced by older people in caregiving training. Two different approaches aiming to free the older people’s working memory space were discussed. They include multi-modal visual processing and Gc activation. The emphasis was on the theor [...]