Table of Content

Open Access Communication

Medical Hypothesis: Deep Brain Stimulation for Intractable Migraine

Received: 26 October 2020;  Published: 05 January 2021;  doi: 10.21926/obm.neurobiol.2101082


Deep Brain Stimulation (DBS) has been introduced as an innovative treatment for several neurological disorders, including Parkinson’s disease, essential tremor, and dystonia and it has been proven effective in helping individuals affected by these disorders; hence, enhancing their quality of life. D [...]

158 741

Open Access Editorial

Acknowlegement to Reviewers of OBM Neurobiology in 2020

Received: 04 January 2021;  Published: 05 January 2021;  doi: 10.21926/obm.neurobiol.2101081


The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions thro [...]

119 575

Open Access Review

The Therapeutic Potential of the Stem Cell Secretome for Spinal Cord Repair: A Systematic Review and Meta-Analysis

Received: 26 October 2020;  Published: 14 December 2020;  doi: 10.21926/obm.neurobiol.2004080


There is currently no effective treatment for spinal cord injury leaving around 90% of patients with permanent disabilities. Stem cell therapies are showing promise in preclinical studies of central nervous system injury and there is increasing evidence suggesting the improvements in functional reco [...]

163 966

Open Access Case Report

Psychiatric Disorders in Mӧbius Sequence: Intermittent Presentation of Auto-Aggressive Outbursts

Received: 27 March 2020;  Published: 03 December 2020;  doi: 10.21926/obm.neurobiol.2004079


Anecdotal evidence suggests the possible association of psychiatric disorders with Mӧbius sequence, although the evidence is not conclusive. Intermittent presentation of auto-aggressive outbursts, in particular, could be related to Mӧbius sequence, different from the common psychotic symptoms. The p [...]

187 713

Open Access Original Research

Variations in Secondary Health Resource Utilization Post Clozapine Initiation

Received: 10 September 2020;  Published: 26 November 2020;  doi: 10.21926/obm.neurobiol.2004078


This study looked at secondary care utilization metrics as an effectiveness indicator of Clozapine initiation in 77 patients over the following year compared to the year prior to initiation. It was found that there was a marginal drop in psychiatric bed utilization, alongside reduced crisis team use [...]

206 698

Open Access Research Article

Transcriptome Signatures of Dysregulated Brain Dynamics Induce Entangled Network States.

Received: 15 June 2020;  Published: 30 December 2020;  doi: 10.21926/obm.neurobiol.2004077


Marks of brain disorders may be visible through abnormal networks characterized by states with distinct signatures or connectivity patterns. Apart from neurodegenerations, drug abuse or eventually addiction may exert complex perturbative effects over human health, including damage to various organs [...]

125 575

Open Access Review

Palmitoylethanolamide for Neurological Disorders

Received: 04 October 2020;  Published: 30 December 2020;  doi: 10.21926/obm.neurobiol.2004076


Neurological tissue along with the cartilage remains one of the tissues that escapes human efforts of regeneration after injury. The human body, after an injury, can repair its tissues only to a certain extent that can help in recovering the function of organs. However, this is not the case in some [...]

137 578

Open Access Review

Peripheral Nerve Dysfunction after Spinal Cord Injury

Received: 02 October 2020;  Published: 29 December 2020;  doi: 10.21926/obm.neurobiol.2004075


Spinal cord injury (SCI) leads to an immediate loss of sensory and motor function below the level of injury mostly affecting people in the prime of life. In addition to the primary injury there is accumulating neurophysiological and histological evidence of dysfunction in the peripheral nerves, not [...]

127 709

Open Access Review

Celiac Disease and Associated Extraintestinal Manifestations, with Special Reference to Neurological Disorders

Received: 13 July 2020;  Published: 30 October 2020;  doi: 10.21926/obm.neurobiol.2004074


Celiac disease (CD), also known as gluten-sensitive enteropathy and nontropical sprue, is one of the most important entities of the wide spectrum of gluten-related disorders (GRDs). It is well known that neurological manifestations can be present either at the onset of CD, or appear during the devel [...]

177 902

Open Access Case Report

A Case of Coincidental Association of Amyotrophic Lateral Sclerosis in a Patient with Celiac Disease Consuming a Gluten-Free Diet

Received: 30 June 2020;  Published: 12 October 2020;  doi: 10.21926/obm.neurobiol.2004073


We report, for the first time, the case of amyotrophic lateral sclerosis (ALS) onset in a 54-year-old woman not following a strict gluten-free diet (GFD) for six years after the diagnosis of celiac disease (CD). The patient did not display any sign of gluten toxicity, malabsorption, or CD-related co [...]

206 880