Maribavir for Management of Cytomegalovirus in Lung Transplant Recipients: A Case Series and Literature Review
Abstract
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Maribavir for Management of Cytomegalovirus in Lung Transplant Recipients: A Case Series and Literature ReviewAbstract Lung transplant recipients represent a high-risk group for cytomegalovirus (CMV) infection and disease, even among solid organ transplant (SOT) recipients, due to multiple factors. Additionally, CMV has significant consequences in this group including pneumonitis, acute rejection, and chronic lung a [...] 111 903 |
Acute Liver Failure Due to Assumed Drug Induced Liver Injury but Lack of Any Validated Causality Algorithm: Evidence by 36 Cohort Reports with 21,709 Casesby
![]() ![]() Abstract Liver transplantation (LT) can be the only option for patients with acute liver failure (ALF) where medical approaches are ineffective. Causes of ALF are multiple and commonly easily detectable, but uncertainty remained on the role of drug-induced liver injury (DILI) within the published ALF cohorts [...] 142 888 |
Embracing Time: The (Dis)Comfort of Life After Allogeneic Stem Cell TransplantsAbstract Allogeneic Stem Cells Transplantation (ASCT) and, consequently, the chronicity associated with this life event has a growing prevalence and a significant impact on the life and daily life of each person who experiences it. The growing number of ASCT survivors highlights the need to reflect on the un [...] 95 768 |
Versatility of the Axillary Intra-Aortic Balloon Pump in Adult Cardiac SurgeryAbstract The axillary intra-aortic balloon pump (ax-IABP) has been proposed as an alternative to the femoral IABP, particularly for patients with comorbidities rendering them unsuitable for fem-IABP insertion. Patient mobilisation with the ax-IABP in situ is deemed an additional potential benefit. We reviewe [...] 100 731 |
Efficiency of Pre-Expanded Anterior Supraclavicular Artery Pedicled Skin Flaps: A Meta-Analysis StudyAbstract The supraclavicular artery flap presents a promising solution for facial reconstruction challenges since 1997, surpassing limitations of traditional methods like the deltopectoral flap. Its extended pedicle and thin, pliable epidermis offer reliable outcomes with minimal donor site morbidity, making [...] 99 832 |
Leukocytosis is Common Following Pediatric Liver Transplant for Biliary Atresia but Should be Interpreted with CautionAbstract Infection is a leading cause of short-term morbidity and mortality in pediatric patients after liver transplant (LT). Diagnosing infection in this population can be challenging, requiring consideration of laboratory results and clinical context. The prevalence and significance of post-operative leuk [...] 90 904 |
Acknowledgement to Reviewers of OBM Transplantation in 2024Abstract The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize rev [...] 95 756 |
Tacrolimus Therapeutic Response, Pharmacokinetics and Adherence in Liver Transplant Recipientsby
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract Background:
Tacrolimus is characterized by a high intra and interindividual pharmacokinetics variability. Data regarding factors that may influence its pharmacokinetics and pharmacodynamics in liver transplantation are limited.
The objectives of this study were to assess tacrolimus therapeutic respo [...] 144 1115 |
A Phase I/II Randomized Trial of Higher Dose mRNA-1273 Boosters in Lung Transplant Recipientsby
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract Higher-dose mRNA booster vaccines have not been well studied for transplant recipients. This study evaluated the safety, reactogenicity and immunogenicity of higher dose mRNA-1273 booster vaccines among lung transplant recipients (LTRs). This phase 1/2 open-label randomized clinical trial of higher- [...] 192 1282 |
Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Fanconi Anemia: Results of a Single Center with a Fludarabine-Based Conditioning Regimenby
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) remains the only curative treatment for bone marrow failure (BMF) and hematologic complications of Fanconi anemia (FA). The evolution remains affected by the toxicity, the risk of graft failure, and clonal evolution. This stu [...] 433 1894 |