by Roy G Beran

Received: 30 November 2022;  Published: 13 February 2023;  doi: 10.21926/obm.geriatr.2301223

This paper reviews the relationship between RBD and PD and the pathophysiology. Most RBD patients develop PD within 14 years. PD pathophysiology is α-synucleinopathy with dopamine degeneration in nigrostriatal pathways. RBD pathology is poorly understood. Anomalies suggest RBD and PD are different, evidenced by smoking. RBD and PD are associated with glucocerebrosidase gene mutations (GBA gene), suggesting RDB with GBA gene mutation predicts PD. PET imaging, assessing vesicular monoamine transporter 2 (VMAT2), inde [...]

by Katharina Reichelt  , Ewan James  , Daniel Thompson  and Shaun Tanney

Received: 14 August 2022;  Published: 18 January 2023;  doi: 10.21926/obm.geriatr.2301222

This article discusses the findings from a training programme called ‘Communication and Interaction Training’ (CAIT). CAIT was designed to improve the confidence of carers in their use of communication skills with people living with dementia, particularly when managing behavioural agitation. This pre/post assessment study employed a mixed design, and showed positive effects in terms of quantitative and qualitative features. The participants were mainly from a specialist team who were experienced in managing episode [...]

by OBM Geriatrics Editorial Office

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/obm.geriatr.2301221

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition dire [...]

by Gopi Battineni  , Mohammad Amran Hossain  , Nalini Chintalapudi  , Giulio Nittari  , Ciro Ruocco  , Enea Traini  and Francesco Amenta

Received: 29 June 2022;  Published: 03 January 2023;  doi: 10.21926/obm.geriatr.2301220

The increasing incidence of adult-onset dementia disorders and primarily Alzheimer’s disease (AD) among the aging population around the world is increasing the social and economic burden on society and healthcare systems. This paper presents three neural networking algorithms: MobileNet, Artificial Neural Networks (ANN), and DenseNet for AD classification based on MRI imaging data. The results of each model were compared in terms of performance metrics such as accuracy, true positive rate, and receiver operating cu [...]

by Helena Andrade Figueira  , Olivia Andrade Figueira  , Alan Andrade Figueira  , Carlos Roberto Lyra da Silva  , Joana Andrade Figueira  and Estelio Henrique Martin Dantas

Received: 14 October 2022;  Published: 29 December 2022;  doi: 10.21926/obm.geriatr.2204219

The World Health Organization attracted more attention to the positive effects of physical activity (PA) and the adverse effects of stress on the health of older people and, therefore, attracted a more significant number of practitioners. To verify the impact of PA on stress in older people. Observational and analytical research, composed of 690 older people of both genders residing in Brazil, present in street races (as participants or observers), who volunteered to respond to the research protocol consisting of s [...]

by Weiyun Chen  , Zhanjia Zhang  , Bruno Giordani  and Janet L. Larson

Received: 03 July 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204218

Physical activity is essential to delaying cognitive decline and preventing cognitive impairment in older adults. We designed and implemented two-level 4Active intervention for older adults living in retirement communities. This study aimed to examine the effectiveness of the 4Active intervention in increasing physical activity and cognitive function in older adults. Fifty-eight eligible older adults with a mean age of 83.83 years (76.3% females) living in two retirement communities voluntarily participated in this [...]

by Howard Litwin  and Bracha Erlich

Received: 26 June 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204217

This study examined the correlates of change in the depressed state among people aged 65 and older during the SARS-CoV-2 pandemic, particularly the effects of crucial pandemic-related variables. Data were drawn from the longitudinal Survey of Health, Ageing and Retirement in Europe (SHARE), including information obtained from two special pandemic-related telephone interviews (N = 18, 266). The analysis regressed depressed state soon after the outbreak (T1) and again a year later (T2), on four pandemic-related varia [...]

by Yogendra Keche  , Preetam Wasneek  , Keshao Nagpure  , Nitin Gaikwad  , Suryaprakash Dhaneria  , Sabah Siddiqui  and Apoorva Joshi

Received: 22 August 2022;  Published: 11 December 2022;  doi: 10.21926/obm.geriatr.2204216

The COVID-19 pandemic had imposed a city-level quarantine, local lockdown, and border closures for patient-level isolation to control virus spread. There is a lack of studies on the health-related quality of life (HRQoL) in the elderly in countries like India during COVID-19. After obtaining written informed consent from the elderly patients, data was recorded in the case record form-cum-questionnaire. The quality of life was assessed with the help of Centers for disease control and prevention (CDC) HRQoL-14 measur [...]

by Athina Markouizou  , Evrydiki Michali  , Christina Mamareli  , Jane Anastassopoulou  , Panayiota Kolovou  , Ioannis Mamarelis  and Theophile Theophanides

Received: 12 September 2022;  Published: 24 November 2022;  doi: 10.21926/obm.geriatr.2204215

Breast cancer affects the female population worldwide. Radiotherapy (RT) is part of the therapeutic modality in the management of breast cancer, after radical mastectomy or conserving surgery. The FTIR spectroscopic “marker bands” will lead us to approach the mechanism of skin damage due to the interaction of ionizing radiation and skin, on a molecular level at the very early stages. FT-IR spectroscopy, breast digital pictures, and ImageJ software were used in the study. Healthy breast skin was irradiated ex-vivo w [...]

by Vikas Dhikav  , Pankaj Kumar  and Praveen Kumar Anand

Received: 23 August 2022;  Published: 23 November 2022;  doi: 10.21926/obm.geriatr.2204214

Various grades of cognitive impairment generally occur in older adults over the age of 55, where cardiovascular risk factors such as diabetes and/or hypertension, coronary artery disease, or cerebrovascular accidents are also common. Cognitive impairment occurs in various forms, from mild or amnesia such as forgetting today's date to more ominous and progressive forms, such as frank dementia. Over 5 million people worldwide suffer from dementia, most of whom live in low- and middle-income countries. It has been env [...]