Co-administration of Zingiber officinale Extract and Sodium Valproate Ameliorates Seizure Severity, Cognitive Deficit, and Neuronal Cell Loss in Pentylenetetrazole-kindled Mice







Abstract
605 6173
Co-administration of Zingiber officinale Extract and Sodium Valproate Ameliorates Seizure Severity, Cognitive Deficit, and Neuronal Cell Loss in Pentylenetetrazole-kindled Miceby
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract
Preparations of Zingiber officinale are used in Nigerian folk medicine to manage colds, pain, arthritis, nausea, and epilepsy. The ameliorative effects of co-administering aqueous Zingiber officinale extract (GE) and sodium valproate (SDV) on pentylenetetrazole-kindled mice were evaluated regarding cognitive deficits, neuronal cell loss, and seizure severity. GFAP was also quantified. Male mice were pretreated with GE (50 mg/kg), SDV (100 and 200 mg/kg), and GE + SDV before kindling. After kindling, the mice underw [...] 605 6173 |
Photobiomodulation Therapy (PBMT) is Feasible and Acceptable in Pre-conditioning and Post-operative Recovery of Patients after Total Knee arthroplasty (TKA): A Clinical Case SeriesAbstract
Photobiomodulation therapy (PBMT) for minimal to moderate Kellgren and Lawrence grade knee osteoarthritis has significant evidence for effectiveness. The effect of PBMT in severe grades of osteoarthritis is less clear; and no studies have investigated the effect of PBMT before and after knee replacement surgery. This small study (n=4) aimed to understand the potential feasibility of undertaking a future randomised controlled clinical trial of a self-administered, home-based light patch system before and after total [...] 741 15785 |
Holy be the Lay: A Way to Mindfulness Through Christian PoetryAbstract
Mindfulness practices have exploded in popularity in public awareness and in therapeutic applications. While mindfulness in a therapeutic context is presented as a secular practice, its primarily Buddhist heritage may make some Christian clients wary of engaging. Research indicates that both reflection (co-creation) on poetry and creation of poetry can be therapeutic, and that both Buddhist and secular/therapeutic mindfulness texts use poetry to convey meaning through key themes of nature, change/impermanence, stag [...] 676 6450 |
Cluster Sets for Muscle Hypertrophy: A Short Review †by
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract
Cluster-set resistance training is focused on performance improvements of sports by increasing the repetition maximum, jump height, and efficiency in the sprint. In this commentary, we present relevant aspects to optimize the use of cluster training under the context of muscle hypertrophy. Therefore, we address intra-sets pauses, the number of repetitions per block, and strategies that benefit this methodology. During a cluster set resistance training program, not only the total number of repetitions could be highe [...] 1188 13647 |
Mindfulness in Well-Being, Cognition and Learning: Benefits on Higher Education and Health-Care ProfessionsAbstract
Mindfulness is a form of meditation that can be defined as one’s ability to be present to the surroundings and environment, and not overreact to what is happening around us. With the recent pandemic still affecting the world, more studies have recently become known describing the suitability of mindfulness to prevent and manage mental health. This fact alone offers grounds for mindfulness practices to be added to any stressful environment, including Institutions of higher education and the workforce. Even more, min [...] 831 8322 |
Experimental Phenomenology as Personalized Health Intervention: A Case IllustrationAbstract
Experimental phenomenology is the investigation of phenomenological practices and their effects. To engage in a phenomenological practice means to focus attention on aspects of one’s experiences (e.g., sense impressions or body sensations) while adopting a specific kind of attitude (e.g., an explorative attitude) according to some set of instructions. The basic assumption is that the regulation of attention and attitudes involved in such practices may have effects on people’s health and quality of life. The present [...] 631 6351 |
Kidney Transplantation during the COVID-19 Pandemic: From Past through Present Time of Emerging Vaccineby
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract
The novel coronavirus disease 2019 (COVID-19) pandemic has significantly impacted kidney transplantation worldwide. The rate of kidney transplantation decreased during the peak of the COVID-19 pandemic, especially living donor kidney transplantation. Kidney transplant recipients are at high risk of developing severe complications from COVID-19 due to underlying comorbidities and immunosuppressed status. Management of immunosuppression, including the induction therapy and maintenance immunosuppressive regimen, has b [...] 981 9749 |
Mothers’ Strategies for Promoting Children’s Healthy Eating, Physical Activity, and Screen-Related BehaviorsAbstract
Parents model and teach early health practices that persist into adulthood by establishing a family culture through which children learn related family beliefs, values, and expectations. This phenomenological study examined the ways in which a purposefully selected group of mothers (selected due to their high scores on the Family Nutrition and Physical Activity screening tool) shaped family culture related to physical activity, addressed screen-time behaviors, and established positive eating related routines. Findi [...] 603 6011 |
Sensorimotor Therapy Using Vestibular Stimulation: A Complementary Method for ‘Treatment’ of Developmental Coordination Disorder and a Possible Way to Awaken the Innate Potential for a Physically Active LifeAbstract
The aim of this commentary is to present characteristics of an “unidentified psychological barrier,” which we previously have speculated to be associated with vestibular underachievement, an overlooked part for the understanding of the resistance to physical activity as well as in the assessments and interventions of developmental coordination disorder (DCD). Furthermore, we will discuss the importance of its identification and how to push knowledge forward. A delayed or partly absent sensorimotor development for a [...] 918 8693 |
An Interview with Dr. Paul J. ArcieroAbstract
Interview with Dr. Paul J. Arciero. Precision lifestyle medicine and implementation science are the emerging frontiers of research in his field. He is an applied physiology and nutrition scientist, specializing in evidence-based scientific research on integrative and complementary lifestyle strategies to optimize health, wellness, and performance in individuals and organizations of all ages, fitness and health status. Specifically, his PRISE® Life protocol emphasizes a qualitative approach to nutrition, fitness, an [...] 582 5793 |
TOP