A Narrative Review on the Use of Eye-Tracking in Rett Syndrome: Implications for Diagnosis and TreatmentAbstract Rett syndrome (RTT) is a rare neurodevelopmental disorder primarily affecting females, characterized by a spectrum of debilitating symptoms that impact neurological, cognitive, and motor functions. Eye-tracking technology (ETT) has emerged as a prominent tool in Augmentative and Alternat [...] 383 2919 |
Causes of Chromosome Breakage and Mis-segregation Affecting Pregnancy and Newborn Health: An Insight into Developing Reproductive Health Preventive Strategiesby
Oyovwi Mega Obukohwo
,
Peggy Ejiro Ohwin
,
Rotu Arientare Rume
,
Olowe Gideon Temitope
,
Oyelere Abosede Oreoluwa
and
Adelowo Joy Motunrayo
Abstract Chromosome abnormalities are a leading cause of pregnancy loss, developmental delays, and birth defects. These abnormalities arise from errors in chromosome structure (breakage) or number (missegregation) during cell division. Understanding the causes of these errors is crucial for devel [...] 417 3106 |
Hormonal and Physiological Manipulation Methods to Induce Polycystic Ovary in Rodents: A Review of the New FindingsAbstract Polycystic ovary syndrome (PCOS) is the most common endocrinopathy causing non-ovulation infertility in women. Women with PCOS have higher levels of luteinizing hormone (LH), testosterone, cholesterol and triglycerides but, in contrast, lower levels of follicular stimulating hormone (FSH) and sex ho [...] 378 2746 |
Chromosome 7 Isodisomy in a Child with Silver-Russell Syndromeby
Luis A. Méndez-Rosado
,
Alicia Vaglio
,
Roberto Lardoeyt- Ferrer
,
Albertino Candimba-Sebastiao
,
Judith Pupo-Balboa
,
Ivan Y. Iourov
and
Alejandro Esperon
Abstract Silver-Rusell syndrome is a rare genetic disease. There is evidence that the genetic causes of the disorder are heterogeneous, with predominant alterations in the imprinted regions of chromosomes 11 and 7, in addition to other genomic alterations, such as chromosomal structural aberratio [...] 354 2375 |
Investigating the Genetic Basis of Unexplained Infertility and Potential Chromosomal AbnormalitiesAbstract Infertility affects millions globally, with 10-15% of couples experiencing unexplained cases. Despite advancements in medicine, the cause remains unknown, causing emotional distress. Recent research suggests a genetic basis for this issue. This review aims to provide a better understanding of the un [...] 493 3585 |
Physico-Chemical Study of the Anti-Diabetic Drug of [BzN-EJJ-amide] for Treatment Type2 Diabetes Using CNT Sensor by Drug Delivery MethodAbstract The potential and selective inhibitors of protein tyrosine phosphatase 1B (PTP1B) are therapeutically useful in treating type 2 diabetes. N-Benzoyl-L-glutamyl-[4-phospho [...] 324 1998 |
Establishment of an In Vitro Propagation, Transformation, and Gene Editing System in Tomato (Solanum lycopersicum)Abstract Tomato (Solanum lycopersicum), a family of Solanaceae, is an annual crop grown in fields and greenhouses. Tomato is the fourth-largest agricul [...] 444 2989 |
Integrated Web Application (Snips2HLA-HsG) Development for Sample Preparation and Model Creation for HLA Allele Prediction with the SNP Data Using HIBAG Package of Bioconductor and R ProgrammingAbstract The present study introduces Snips2HLA-HsG, an integrated application designed for SNP genotype analysis and HLA allele type prediction. Leveraging attribute bagging, a powerful ensemble classifier technique from the Bioconductor HIBAG package, Snips2HLA-HsG offers a comprehensive response for genet [...] 341 2859 |
Melatonin As a Protective Agent Against Environmental Stresses: A Review into Its Molecular Regulation in Plantsby
Buti Obaid Saeed Alfalahi
,
Imane Lamdjad
,
Noaman Atallah Alheety
,
Mustafa Alnujaifi
and
Abdul Qayyum
Abstract Understanding the impact of melatonin (N-acetyl-5-methoxytryptamine) on plant gene expression is crucial for unlocking its full potential as a tool for crop improvement and stress tolerance. Melatonin has emerged to have several influences on the transcriptional activity of numerous genes, helping t [...] 343 2365 |
The Screening Strategies Used to Establish Egyptian Women Entrepreneurs’ Attitudes towards Genetic TechnologyAbstract In this quantitative study, the researcher examined the screening strategies used to establish Egyptian women entrepreneurs' attitudes toward genetic technology. Using a questionnaire, the researcher collected data from 318 Egyptian women entrepreneurs. From applying the path analysis through Analys [...] 407 2101 |