Molecular Marker Applications in the Selection of Elite Genotypes for Plant Stress Tolerance and Genetic FidelityAbstract Molecular markers play a crucial role in accelerating crop production for sustainable agriculture by identifying resistant traits and enhancing genetic diversity. In this review, we examine the impact of the molecular markers on advancing our understanding of stress tolerance mechanisms [...] 407 2714 |
Unique Female Patient with de novo 6q22.31q27 Duplication and Xq28 Deletion: Case Report and Brief Literature Reviewby
Lamiae Afif
,
Zhour El Amrani
,
Aziza Sbiti
,
Ilham Ratbi
,
Imane Cherkaoui Jaouad
,
Youssef El Kadiri
,
Thomas Liehr
,
Abdelaziz Sefiani
and
Abdelhafid Natiq
Abstract 6q22.31q27 duplication and Xq28 deletion lead to two specific different rare chromosomal disorders. Partial trisomy 6q22.31q27 is a recognizable syndrome with a distinctive phenotype, and the most common finding in girls with Xqter deletions has been premature ovarian failure (POF) and s [...] 356 2026 |
Case Studies in the Ethics of Assisted Reproduction, by Louise P. King & Isabelle C. Band, Switzerland: Springer Cham, 152 Pages, Ebook, 978-3-031-41215-8Abstract "Case Studies in the Ethics of Assisted Reproduction" explores the moral and ethical implications of assisted reproductive technologies (ART), such as in vitro fertilization (IVF), surrogacy, and genetic screening. These findings outline ethical dilemmas, including the importance of inform [...] 306 2144 |
A Child Carrying a Large Deletion in the 10p.15.3-p12.31 RegionAbstract Partial deletion of 10p is a rare disorder. Common features of this disorder include intellectual disability, developmental delay, dysmorphic features, hypoparathyroidism, deafness, and renal anomalies, but the phenotypes can vary between patients. We report an infant girl presented with global deve [...] 250 1932 |
Phenylketonuria—Past, Present, and Future Directionsby
Nicole A. Bailey
and
Laura Mackay
Abstract Phenylketonuria (PKU) is an autosomal recessive inborn error of metabolism with an incidence that varies throughout the world. PKU is caused by loss of function variants in the phenylalanine hydroxylase gene. This loss of function leads to the accumulation of an amino acid, phenylalanine [...] 425 4036 |
Miscarriages after Natural Conception & IVF: Comparative Study of Genetic Analysis of Products of Conceptionby
Elena V. Kudryavtseva
,
Sergey N. Fedenev
,
Ilia V. Kanivets
,
Anastasiya N. Troitskaya
and
Vladislav V. Kovalev
Abstract Assisted reproductive technologies (ART), including in vitro fertilization (IVF), are modern medical technologies widely used in developed countries. A frequent complication of pregnancy resulting from ART is miscarriage. The leading cause of miscarriage, both sporadic and recurrent, is [...] 280 2198 |
Exploring Multitargets Treatment for Diabetesby
Bolanle Adenike Akinsanola
,
Matthew Iyobhebhe
,
Tobiloba Christianah Maduakolam-Aniobi
,
Tomilola Debby Olaolu
,
Damilare Emmanuel Rotimi
and
Oluwafemi Adeleke Ojo
Abstract Diabetes Mellitus (DM) is a degenerative disease that modifies the body’s glucose metabolism. Although glucose is a vital energy source for body cells, individuals with diabetes can either not use insulin efficiently or do not create enough of this hormone, which controls blood sugar. &l [...] 240 2066 |
Blinatumomab vs Chemotherapy for Pediatric and Adult Acute Lymphoblastic LeukemiaAbstract Several therapeutic methods are used to cure acute lymphoblastic leukemia (ALL). Relapsed/refractory B-cell ALL (R/R B-ALL) remains the primary cause of death worldwide due to the [...] 381 2493 |
Potential Use of Human Mesenchymal Stem Cells (hMSCs) in Pancreatic Damage/CancerAbstract Pancreatic damage and pancreatic cancer pose significant challenges due to their complex pathogenesis, limited treatment options, and poor prognosis. In recent years, the potential use of human Mesenchymal Stem Cells (hMSCs) has been explored to address these complex pancreatic conditions and develo [...] 359 2192 |