OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Indexing: 
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Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 12 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period). 

Open Access Review

Heart Failure in Elderly People: From Pathophysiology to Diagnosis and Management

Received: 05 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.geriatr.2303250

Abstract

As the older population increases, there is an increase in age-related chronic diseases, especially heart failure. It affects 25% of over 75-year-old outpatients and represents the leading cause of hospitalization and death in older people. This review aimed to point out the main characteristics concerning heart failure in older people, taking into [...]

Open Access Short Communication

Redefining Hypotension in Older Adults: Implications for the Prevention of Age Related Cognitive Decline

Received: 24 April 2023;  Published: 18 September 2023;  doi: 10.21926/obm.geriatr.2303249

Abstract

Chronically low blood pressure in older adults is associated with significantly increased long-term risks of dementia and all-cause mortality risk. Yet low blood pressure is generally not treated until an individual begins to experience the acute symptoms arising from very low cerebral perfusion. However, these acute symptoms, such as dizziness, balance [...]

Open Access Editorial

Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges

Received: 31 August 2023;  Published: 13 September 2023;  doi: 10.21926/obm.geriatr.2303248

Abstract

In the United States (US), menopause occurs at an average age of 52. Menopausal symptoms tend to be maximal during the few years before and the year after menopause (during perimenopause), except for symptomatic vulvovaginal atrophy, which may worsen over time. Up to 20% of bone density loss occurs during the first 5 years after menopause, followed [...]

Open Access Opinion

Life-Changing Bubbles: A Simple Solution That May Help Many

Received: 20 February 2023;  Published: 24 August 2023;  doi: 10.21926/obm.geriatr.2303247

Abstract

As the medical world continues to search for ways of improving the swallowing of many millions of Dysphagia sufferers around the world, this paper is devoted to presenting the case for carbonated water to be considered as a potential solution for many. The effectiveness of carbonated water (CW) in the rehabilitation of Dysphagia has been studied periodi [...]

Open Access Short Communication

US State Hospital Regulations Rarely Include Malnutrition but Could Provide a Future Policy Framework for Improving Malnutrition Quality of Care

Received: 31 March 2023;  Published: 17 August 2023;  doi: 10.21926/obm.geriatr.2303246

Abstract

Malnutrition is a problem that is often not identified in hospitals as 8% of hospital patients are diagnosed but malnutrition is estimated to affect 20-50% of patients. Federal programs such as Joint Commission accreditation and the new, optional, global malnutrition composite score from CMS may improve inpatient malnutrition diagnosis, but there ma [...]

Open Access Research Article

Comprehensive Geriatric Assessment of Elderly Adults

Received: 23 March 2023;  Published: 14 August 2023;  doi: 10.21926/obm.geriatr.2303245

Abstract

The geriatric population is increasing all over the world. Aging people have special health requirements and comprehensive medical checkups prevent physical, functional and mental decline during the aging period. This study aimed to examine the fitness level and identify problems with the well-being of elderly persons. In this context, the study also [...]

Open Access Perspective

Vascular Risks, Aging, and Late-Onset Dementia: Overlapping Etiologies Point to 'Scavenger Receptor'-Mediated Therapeutics

Received: 25 March 2023;  Published: 04 August 2023;  doi: 10.21926/obm.geriatr.2303244

Abstract

Early changes in systemic vascular stiffness and endothelial function can contribute to altered cerebrovascular hemodynamics and impaired cognitive function; additionally, these vascular changes point to potential targets for prevention and treatment strategies in people with mild cognitive impairment. Although the pathogenic mechanisms underlying these [...]

Open Access Research Article

AI Literacy for an Ageing Workforce: Leveraging the Experience of Older Workers

Received: 02 March 2023;  Published: 25 July 2023;  doi: 10.21926/obm.geriatr.2303243

Abstract

This study delves into the potential benefits of Artificial Intelligence (AI) literacy training for late-career-stage workers approaching retirement. These workers often possess extensive experience but may lack the necessary digital and AI skills. AI literacy training can empower them to leverage their experience and become proficient contributors [...]

Open Access Short Communication

Cross-Temporal Patterns of Care Provision by Older Adults during COVID-19 Pandemic: Lessons for Resilience

Received: 13 March 2023;  Published: 11 July 2023;  doi: 10.21926/obm.geriatr.2303242

Abstract

The current study aimed to examine the link between cross-temporal patterns of care provision and loneliness in older adults. Social capital and caregiver stress perspectives served as a theoretical framework for the study. The data were obtained from the two COVID-19 waves of the Survey of Health, Ageing, and Retirement in Europe (SHARE) conducted [...]

Open Access Interview

An Interview with Dr. Ines Testoni

Received: 25 June 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302241

Abstract

InterviewAn Interview with Dr. Ines TestoniOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2023, volume 7, issue 2 doi:10.21926/obm.geriatr.2302241Received: June 25, 2023Accepted: June 26, 2023Published: June 27, 2023

Open Access Case Report

Polymyalgia Rheumatica Evolved into RS3PE Syndrome. What is the Culprit: Idiopathic or Secondary, Following mRNA-Based COVID-19 Vaccines? A Case Report and Brief Review of the Literature

Received: 08 January 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302240

Abstract

We describe the clinical case of a 74-year-old male patient who received the second Comirnaty/Pfizer anti-COVID-19 vaccine dose. After 3 weeks he showed the clinical signs of polymyalgia rheumatica. The history included mild chronic normocytic normochromic anemia and hypogammaglobulinemia, osteoarthritis disease, livedo reticularis, hypercholesterolemia [...]

Open Access Original Research

Role of Activity Professionals in Applying APIE Model to Enhance Residents’ Activity and Engagement in Long-Term Care Settings

Received: 23 August 2022;  Published: 25 June 2023;  doi: 10.21926/obm.geriatr.2302239

Abstract

Residents’ activity is a strong contributor to the quality of life in long-term care facilities. Hence, activity professionals have an essential role to play in enhancing residents’ activity engagement. Professional practice model for activity professionals includes Assessment, Planning, Implementation, and Evaluation (APIE model). Although activit [...]

Open Access Original Research

The Geriatric Impact in the Management of Complex Cancer Patients: A Monocenter Experience

Received: 17 November 2022;  Published: 13 June 2023;  doi: 10.21926/obm.geriatr.2302238

Abstract

New technologies, aging-related changes, and evolution in patients' needs have led to a new scenario in all oncological fields in front of which we have to move on. Technological progress has made it possible to increase the number of patients treated, including elderly patients and generally those at higher risk of toxicity. However, this scenario [...]

Open Access Communication

The Global Malnutrition Composite Score Quality Measure-Seize this Opportunity to Benefit Older Adult Care and Health Equity!

Received: 27 February 2023;  Published: 25 May 2023;  doi: 10.21926/obm.geriatr.2302237

Abstract

In August 2022, the Centers for Medicare and Medicaid Services (CMS) adopted its first-ever nutrition electronic clinical quality measure (eCQM), known as the Global Malnutrition Composite Score (GMCS) as part of the Inpatient Hospital Quality Reporting (IQR) Program. Starting in January 2024, hospitals can self-select to include the GMCS as one of [...]

Open Access Review

The Effects of Loneliness on the Aged: A Review

Received: 09 November 2022;  Published: 17 May 2023;  doi: 10.21926/obm.geriatr.2302236

Abstract

Social support has been shown to have many positive effects on our lives, health, and ability to grow and flourish. Lack, or diminished social support results in loneliness. This thematic review focuses on the elderly, and the loneliness that is part of the life of many of them. The review highlights the social connections and the expectations that [...]

Open Access Research Article

Older People and the Construction of Virtual Identities in the Digital Culture

Received: 06 February 2023;  Published: 10 May 2023;  doi: 10.21926/obm.geriatr.2302235

Abstract

This research study addresses certain theoretical issues surrounding the relationship between digital technologies, the aging population, and identity. At the same time, it offers a conceptual proposal of indicators of the social inclusion of older people in the digital culture of society as a potential starting point for further empirical research [...]

Open Access Review

Emerging Roles of Signal Transduction Pathways in Neurodegenerative Diseases. Hunting New Possible Therapeutic Molecular Targets

Received: 27 January 2023;  Published: 05 May 2023;  doi: 10.21926/obm.geriatr.2302234

Abstract

Illnesses following the degeneration of the nervous system can occur due to aging or genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of neuronal structure and functions mainly causes cognitive impairment, representing an increasing social burden. In neurodegenerative diseases, the progressive loss of vulnerable [...]

Open Access Review

Use of Artificial Intelligence in Skin Aging

Received: 02 July 2022;  Published: 17 April 2023;  doi: 10.21926/obm.geriatr.2302233

Abstract

Skin aging is a complex process that involves several extrinsic and intrinsic factors and skin health is an indicator of the well-being of an individual. In recent years, there have been numerous developments using computerized systems to aid in finding solutions and treatments to skin aging processes. Tools like artificial intelligence (AI) can aid [...]

Open Access Editorial

Driving Safety in Healthy Aging and Age-Related Diseases

Received: 03 April 2023;  Published: 04 April 2023;  doi: 10.21926/obm.geriatr.2302232

Abstract

EditorialDriving Safety in Healthy Aging and Age-Related DiseasesMichael Falkenstein *, Ute Brüne-CohrsALA Institute, 44805 Bochum, Germany; E-Mails: falkenstein@ala-institut.de; Ute.Bruene-Cohrs@ruhr-uni-bochum.de * Correspondence: Michael Falkenstein; E-Mail: falkenstein@ala-institut.deSpecial Issue: Driving Safety in Healthy Aging and Age-Related [...]

Open Access Original Research

Differences in Blame-Like and Forgiveness-Like Judgments between Young People, Healthy Older People, and Older People with Dementia

Received: 19 October 2022;  Published: 03 April 2023;  doi: 10.21926/obm.geriatr.2302231

Abstract

The objective of the present experimental study was to compare how young people, healthy older people, and older people with dementia cognitively integrated three factors (Intention, Consequence, and Apology) when making blame-like judgments (prosecution and revenge) and forgiveness-like judgments (resentment and reconciliation). Thirty-four young peopl [...]

Open Access Original Research

Integration between Geriatric Oncology and Palliative Care: A Single Center Experience for Hospitalized Older Patients with Cancer

Received: 26 October 2022;  Published: 27 March 2023;  doi: 10.21926/obm.geriatr.2301230

Abstract

Comprehensive Geriatric Assessment (CGA) is utilized to plan social and health care of the elderly and to complete the diagnostic-therapeutic choice of oncologist also considering early integration with palliative care. Cancer patients (pts) hospitalized aged ≥70 years were screened by the G8 questionnaire to define if necessary CGA. CGA identified: [...]

Open Access Interview

An Interview with Dr. Terry Fulmer

Received: 15 March 2023;  Published: 23 March 2023;  doi: 10.21926/obm.geriatr.2301229

Abstract

InterviewAn Interview with Dr. Terry FulmerOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2023, volume 7, issue 1 doi:10.21926/obm.geriatr.2301229Received: March 15, 2023Accepted: March 15, 2023Published: March 22, 2023

Open Access Short Communication

Evolution of Psychosomatic Diagnosis: From Masked Depression to Somatic Symptoms and Related Disorders

Received: 02 December 2022;  Published: 22 March 2023;  doi: 10.21926/obm.geriatr.2301228

Abstract

This paper discusses the history and the concept of somatization from masked depression to somatic symptoms and related disorders in the Diagnostic and Statistical Manual of Mental Disorders (DSM). Evaluating the evolution of these terms and concepts along the time course is very interesting. DSM 5 revision was intended to increase the relevance of [...]

Open Access Perspective

The Opportunity for Quality Malnutrition Care to Improve Rural Health Outcomes and Health Equity for Older Americans

Received: 22 November 2022;  Published: 10 March 2023;  doi: 10.21926/obm.geriatr.2301227

Abstract

Older adults have a heightened risk of malnutrition that occurs with age. Many factors can increase their risk for malnutrition, including factors associated with disease, function, social and mental health, and hunger and food insecurity. Risk for malnutrition is also linked to disparities and may disproportionately impact people living in rural areas [...]

Open Access Review

Do Antioxidants Extend Longevity in Invertebrate and Vertebrate Animals?

Received: 09 November 2022;  Published: 07 March 2023;  doi: 10.21926/obm.geriatr.2301226

Abstract

In the 1950’s Denham Harman proposed the Free Radical Theory of Aging whereby species lifespan and individual longevities are the consequence of free radical driven damage to biomolecules. This led to decades of research to ascertain the effect of altered antioxidant defense systems on aging and mortality in an array of species using reverse genetics [...]

2nd Mediterranean Congress of Anti-aging Medicine 2022

14–16 October 2022, Larnaca, Cyprus

This is the second time a conference with such a wide-ranging theme on aging is held in Cyprus. The 1st Mediterranean Congress of Antiaging Medicine was held in Larnaca on 13-14 April 2019. The health of older people is a crucial subject which involves a multidisciplinary approach in order to offer effective treatments against age-related diseases. The conference is comprehensive and practical, involving both basic science and clinical therapies. Lectures, presentations and seminars will be delivered by world-class academics, and by clinicians of European prestige. It will be attended by scientists working in the science of aging both from Cyprus and from Europe, Israel, Russia, United Kingdom, as well as clinicians, health professionals and others with interest in applied, effective interventions which may help reduce the impact of aging upon society. We expect wide media coverage as well as publicity reaching European, Asian and American countries.

For more information, visit the official website at: https://mcamcyprus.org/

26th World Congress on Medical Law

December 5th- 7th, 2022, Gold Coast, Australia

The purpose of the WAML is to encourage the study and discussion of health law, legal medicine and ethics, for the benefit of society and the advancement of human rights. The aim of the WAML is to promote the study of the consequences in jurisprudence, legislation and ethics of developments in medicine, health care and related sciences.

Congress Themes:

   1. Impact of Covid on Legal Medicine

   2. Medicine and technology

   3. Concussion and Traumatic brain injury

For more details, please visit: http://wafml.memberlodge.org/, http://lidsen.com/2022 WCML Brochure FINAL.

World CB & CDx 2022

April 27-28, 2022, London, UK

As the precision medicine industry witnesses exciting Drug-Dx approvals being driven by major advancements in biomarker development, the 12th Clinical Biomarker & CDx Summit Europe returns in 2022 to set the stage for key learnings with exclusive data to optimise your drug development programmes with the most cutting-edge tools and techniques from start to finish.

Against the backdrop of complex IVDR changes creating industry-wide uncertainty, CB & CDx Europe returns at an all-important moment in time as Europe’s only end-to-end clinical biomarker and CDx summit. Uniting the entire value chain of precision medicine leaders, here you can find the latest updates, intelligence and clarity to overcome your portfolio planning hurdles.

Delving deep into the most ground-breaking work enabling patient population identification, and pairing this with revelations from streamlined commercial strategies, this is an industry poised to gain actionable insights maximising access to game-changing precision medicines and testing technology in European markets.

Join with 300+ major stakeholders of the European drug-diagnostics field to forge successful scientific and commercialization co-development strategies at a pivotal moment for precision medicine.

For more details, please visit: https://cdx-europe.com/

Alzheimer's Association International Conference

July 31 – August 4, 2022, San Diego, USA and Online

Join us in San Diego and online for AAIC 2022, where the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community will share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease.
For more details, please visit: https://www.alz.org/aaic/overview.asp

International Continence Society

September 07-10, 2022, Vienna, Australia

What to Expect at ICS 2022

ICS 2022 in Vienna will be a great 4-day meeting, offering a range of sessions and topics depending upon your speciality and interests.

The ICS annual meeting brings together the most renowned international experts in the research and the treatment of LUTS, incontinence and pelvic foor disorders. The meeting is multidisciplinary and welcomes urologists, gynaecologists, neurourologists, physiotherapists, nurses, midwives and research scientists.

ICS 2022 State of the Art Lectures and Round Table Debates

Expect to hear from world class leaders in the field of incontinence. Their lectures and discussions will bring you the cutting-edge information about pelvic floor dysfunction. We are pleased to confirm our 2022 State of the Art Lectures.

For more details, please visit:https://www.ics.org/2022

13th Clinical Trials on Alzheimer's Disease (CTAD)

November 4-7, 2020, Boston, USA

The development of the next generation of Alzheimer’s disease treatments is among the most important health needs worldwide, but presents huge challenges. The goal of the meeting is to bring together today’s worldwide leaders in the treatment of Alzheimer’s disease to discuss new results, candidate therapeutics, and methodological issues important to the development of the next generation of Alzheimer’s disease treatments.

Clinical trial teams from worldwide centers will report on their efforts to identify new biomarkers of disease as well as more sensitive clinical assessment tools to identify those at risk for AD, to predict progression, and assess the effectiveness of new treatments.

For more details, please visit: https://www.ctad-alzheimer.com/ctad-2020

Alzheimer's Association International Conference®

July 26-30, 2020, Amsterdam, Netherlands

AAIC 2020 will bring together international investigators, clinicians and care researchers to discuss the latest studies, theories and discoveries that will help bring the world closer to breakthroughs in dementia science.

For more details, please visit: https://www.alz.org/aaic/overview.asp

Integrative Regen Group

February 29- March 2, 2020, Arizona Biltmore Resort, USA

Who: Providers of all disciplines who are passionate about or interested in regenerative medicine are encouraged to attend this event. The agenda will be packed full of actionable topics that most attendees will be able to put into effect immediately to continue to provide their patients with the most cutting-edge therapies.

What: Integrative Regen Group’s second conference will be bringing together experts in all areas of regenerative medicine, from stem cells to photobiomodulation, peptides to hormones, and everything in between. It is our goal that every person in attendance increase their knowledge base substantially.

For more details, please visit: https://www.intregengroup.com/

The 2nd Longevity Therapeutics

January 28-30, 2020, San Francisco CA, USA

With rapid advances in the understanding of the underlying biology and mechanisms of aging, ground-breaking research and technology are coming together to target aging pathways, in a way to prevent, reverse or delay the onset of age-related conditions, and consequently improve heathspan.

The 2nd Longevity Therapeutics 2020 Summit will once again bring together 80+ leading experts in aging-related research, including biotechs, pharma, academics and investors, who are committed to serving worldwide population with innovative drugs to prevent, delay and treat age-related conditions.

For more details, please visit: https://longevity-therapeutics.com/

OBM Geriatrics welcomes the following types of articles: original research, review, communication, opinion, case report, comment, conference report, technical note, book review, etc. There is no restriction on the length of the papers, color figures, supplementary file types. More details please see Instructions for Authors.

Register and Submit now.

Announcement
Newsletter
Highlight

Highlight

by Michael Fossel

OBM Geriatrics 2023

Published: 15 January 2020

Highlight from: A unified model of dementias and age‐related neurodegeneration.

Michael Fossel.

Alzheimer’s & Dementia.

doi: 10.1002/alz.12012.

Highly Accessed Articles

Case Report

by Garuth Chalfont et al.

OBM Geriatrics 2023

Published: 07 August 2019

Perspective

by Robert Conder et al.

OBM Geriatrics 2023

Published: 20 March 2019

Review

by Michael Fossel

OBM Geriatrics 2023

Published: 15 February 2019

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