Open Access Review

Role of Genomics in Neonatal Care and Research—A Narrative Review

Received: 07 April 2024;  Published: 20 December 2024;  doi: 10.21926/obm.genet.2404276

Abstract

There is a high prevalence of genetic abnormalities that significantly contribute to overall morbidity and mortality in neonates. Since early diagnosis is crucial for the optimal administration of conventional and customized medications, neonatal acute care has the most significant potential to benefit from genomic medicine. Genome sequencing has been [...]

Open Access Review

A Systematic Review on the Role of SnRK2 Gene in Arabidopsis thaliana Growth Stages under Abiotic Stresses

Received: 29 August 2024;  Published: 17 December 2024;  doi: 10.21926/obm.genet.2404275

Abstract

This systematic review examines the role of SnRK2 (Sucrose non-fermenting 1-Related protein Kinase 2) genes in Arabidopsis thaliana growth and responses to abiotic stresses. SnRK2 protein kinases are key components of abscisic acid (ABA) signaling and osmotic stress responses in plants. The review synthesizes findings from numerous studies on how differ [...]

Open Access Research Article

How to Keep Doing What You Like Doing: A Qualitative Study of Active Older Adults’ Insights on the Facilitators and Barriers to Maintenance of Physical Activity (From the MOVEAGE-Act Project)

Received: 05 June 2024;  Published: 17 December 2024;  doi: 10.21926/obm.geriatr.2404292

Abstract

While the facilitators/barriers for the initiation of physical activity (PA) are well documented, there is less known about these facilitators/barriers for maintenance of PA in the older population in general and not following an intervention. This study aimed to explore older adults’ perspectives on the facilitators/barriers to maintaining PA. The [...]

Open Access Original Research

Mechanical Characterization of a Tunable 3-D Collagen-Hyaluronic Acid Hydrogel for Use in Cell Culture

Received: 28 June 2024;  Published: 17 December 2024;  doi: 10.21926/rpm.2404028

Abstract

Many cells demonstrate variances in behavior due to their cell culture environment. To provide a mechanically-tunable, tissue-like environment, a 3D hydrogel for cell culture was formulated using collagen (Col) and hyaluronic acid (HA) to help provide a system for studying these dynamic cellular responses in a soft-tissue environment. A design of experi [...]

Open Access Original Research

Tacrolimus Therapeutic Response, Pharmacokinetics and Adherence in Liver Transplant Recipients

Received: 20 August 2024;  Published: 13 December 2024;  doi: 10.21926/obm.transplant.2404228

Abstract

Background: Tacrolimus is characterized by a high intra and interindividual pharmacokinetics variability. Data regarding factors that may influence its pharmacokinetics and pharmacodynamics in liver transplantation are limited. The objectives of this study were to assess tacrolimus therapeutic response, pharmacokinetics and adherence in liver transplant [...]

Open Access Case Report

Prolonged Maintenance of Remission with Crohn Disease Exclusion Diet (CDED) in Two Siblings with Crohn Disease

Received: 23 August 2024;  Published: 13 December 2024;  doi: 10.21926/rpn.2404020

Abstract

Dietary and nutritional interventions have been shown to have roles in managing active Crohn disease (CD), with exclusive enteral nutrition (EEN) being recommended as the preferred initial treatment in children following diagnosis. In recent years, other nutritional interventions such as the Crohn's disease exclusion diet (CDED) have been considered [...]

Open Access Review

Viral/Non-Viral Vectors in DNA/RNA Delivery Technology

Received: 26 August 2024;  Published: 12 December 2024;  doi: 10.21926/rpm.2404027

Abstract

Viral and non-viral vectors for nucleic acids (DNA/RNA) therapeutics are important in development of pharmaceutical industries. Although viral vectors have shown significant impact in transfection of DNA/RNA, but numerus studies have shown that non-viral vectors are also effective for the safe and targeted delivery of DNA/RNA to exact location in the [...]

Open Access Review

Molecular Markers Used to Reveal Genetic Diversity and Phylogenetic Relationships in Crop Plants

Received: 16 June 2024;  Published: 12 December 2024;  doi: 10.21926/obm.genet.2404274

Abstract

Genetic diversity allows plants to adapt to changing environmental conditions to survive and increases their ability to respond to yield, production, pests and diseases. The application of molecular markers developed due to developments in biochemistry, molecular biology, and plant technology has shed light on plant genetics and breeding studies and [...]

Open Access Original Research

The Use, Profile, Uptake, Characteristics and Attributes of Users of Homeopathy: Initial Findings from a Student Teaching Tele-Healthcare Clinic Based in North America

Received: 03 September 2024;  Published: 09 December 2024;  doi: 10.21926/obm.icm.2404069

Abstract

Research into the uptake profile and usage of Homeopathy has hitherto tended to be buried amongst complementary medicine research. Despite high levels of uptake of homeopathy, and robust numbers of over-the-counter sales of homeopathic products the current evidence evaluating the uptake of homeopathy remains limited on several fronts. The aim of this [...]

Open Access Review

A Conceptual Model of Dysphagia in Older Adults

Received: 06 August 2024;  Published: 09 December 2024;  doi: 10.21926/obm.geriatr.2404291

Abstract

A conceptual model was developed to create a basis for understanding the risk factors and outcomes associated with dysphagia and to hypothesize the nature of the relationship between certain factors. The conceptual model was developed by two academic speech-language pathologists with ≥10 years research and clinical experience in swallowing and dysphag [...]

Open Access Original Research

Trace Elements Spatial Distribution in the Groundwater near the Subarnarekha River Basin - Jamshedpur, India

Received: 07 August 2024;  Published: 06 December 2024;  doi: 10.21926/aeer.2404027

Abstract

The present study assessed the spatial distribution of trace elements in the groundwater near the Subarnarekha River Basin - Jamshedpur, India. Half of this city's water need (48.11%) relies on groundwater resources. GIS-based maps were constructed using ArcGIS 10.3 software to describe the spatial distribution of Arsenic (As), Barium (Ba), Cadmium [...]

Open Access Original Research

Energy Policy Scenarios for Carbon Emissions in Road Passenger Transport in Austria up to 2050

Received: 23 June 2024;  Published: 06 December 2024;  doi: 10.21926/aeer.2404026

Abstract

The transport sector currently contributes to about 25% of total CO2-emissions in the EU as well as in Austria. The largest share is caused by individual passenger car transport, primarily powered by fossil fuels. It is imperative to replace conventional cars with sustainable alternative technologies and explore alternative modes of transportation, [...]

Open Access Communication

Important Guide for Natural Compounds Inclusion in Precision Medicine

Received: 25 April 2024;  Published: 06 December 2024;  doi: 10.21926/obm.genet.2404273

Abstract

Precision medicine describes the definition of disease at a higher resolution by genomic and other technologies to enable more precise targeting of disease subgroups with new therapies. Preventative or therapeutic interventions can be developed with the knowledge of how a compound acts safely in the body to target receptors and produce the desirable [...]

Open Access Original Research

High Data Rate MWD Mud Pulse Telemetry – From Mysteries to Discovery

Received: 07 September 2024;  Published: 06 December 2024;  doi: 10.21926/jept.2404023

Abstract

Our new approach to MWD mud pulse telemetry offers significant increases over conventional data rates. Using waveguide acoustics, we show that common drilling communications channels support carrier frequencies exceeding several hundred Hertz. Such signals are prone to attenuation over large drillpipe distances. Low power, self-spinning “turbosiren [...]

Open Access Editorial

MOF-based Heterogeneous Catalysis: A Frontier in Sustainable Chemical Transformations

Received: 02 December 2024;  Published: 05 December 2024;  doi: 10.21926/cr.2404014

Abstract

EditorialMOF-based Heterogeneous Catalysis: A Frontier in Sustainable Chemical TransformationsGirijesh Kumar *Department of Chemistry, University of Allahabad, Prayagraj-211002, Uttar Pradesh, India; E-Mails: girijeshchem@gmail.com; girijeshkumar@allduniv.ac.in* Correspondence: Girijesh Kumar; E-Mails: girijeshchem@gmail.com; girijeshkumar@allduniv [...]

Open Access Original Research

Energy Self-Sufficiency in Rural Areas; Case Study: North Euboea, Greece

Received: 28 August 2024;  Published: 05 December 2024;  doi: 10.21926/aeer.2404025

Abstract

The modern globalized civilization is sustained by interactions, trade, the transportation of goods, and energy. Energy self-sufficiency is crucial in rural and disaster-prone areas like North Euboea because dependence on external energy supplies can leave regions vulnerable to supply chain disruptions, price volatility, and geopolitical risks. In such [...]

Open Access Editorial

Opportunities and Challenges of Molecular Catalysts

Received: 28 November 2024;  Published: 02 December 2024;  doi: 10.21926/cr.2404013

Abstract

EditorialOpportunities and Challenges of Molecular CatalystsAmarachi Nkwoada *Department of Chemistry, School of Physical Sciences, Federal University of Technology Owerri, Imo State, PMB 1526, Nigeria; E-Mails: amarachi.nkwoada@futo.edu.ng; chemistryfrontiers@gmail.com * Correspondence: Amarachi Nkwoada; E-Mails: amarachi.nkwoada@futo.edu.ng; [...]

Open Access Original Research

Mental Health and Quality of Life in Kenyan Youths: Differential Susceptibility to Family Risk

Received: 29 May 2024;  Published: 29 November 2024;  doi: 10.21926/obm.icm.2404068

Abstract

Abstract This cross-sectional study aimed to address the association between parental and family characterics as risk factors for emotional and behavioral problems (EBP) and quality of life (QoL), and the potential moderation of these associations by adolescents’personal characteristics. A total of 533 households from Central Kenya with adolescents [...]

Open Access Review

Nutrition Interventions in Aged Care: The Need and Challenges in the Aged Care Context

Received: 08 May 2024;  Published: 29 November 2024;  doi: 10.21926/rpn.2404019

Abstract

Malnutrition and frailty are preventable and reversible. However, a significant proportion of aged care residents live with malnutrition and frailty which have associated complications such as increased falls, hospitalizations, infections, and decreased quality of life. Nutrition and dietary interventions can prevent these issues, however, there a few [...]

Open Access Review

The Origin of Natural Neurostimulation: A Narrative Review of Noninvasive Brain Stimulation Techniques

Received: 08 September 2024;  Published: 29 November 2024;  doi: 10.21926/obm.neurobiol.2404260

Abstract

This narrative review of the literature on noninvasive brain stimulation techniques observes four neurostimulation domains: light therapy, photobiomodulation, a group of techniques within transcranial electric current and magnetic field stimulations, low-frequency sound stimulations, including vibroacoustic therapy, and rhythmic auditory stimulation [...]

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