Environmental Risk Assessment of Antiretrovirals Consumed in Belo Horizonte, BrazilAbstract The development and utilization of pharmaceuticals, notably antiretrovirals (ARVs), have significantly enhanced both human quality of life and life expectancy. Nevertheless, the excretion of these compounds into aquatic environments, often exacerbated by inadequate sanitation infrastructure, poses considerable risks to biota. This investigation evaluate [...] |
GHG Emissions Management in Urban Areas by Interactive Road Traffic Control: Application of Artificial IntelligenceAbstract The rising pollution levels in congested urban areas pose a serious threat to human health. Many solutions have been proposed to control and reduce gas emissions from road traffic, with results that are not entirely satisfactory. The adoption of new techniques and methodologies for early detection of pollutant emissions may enable effective management [...] |
The Value of Camellia sinensis in the Management of Toxicity Induced by Cancer TreatmentsAbstract While radiotherapy is one of the main treatments for head and neck cancer, adverse effects limit its effectiveness and affect patients' quality of life. Although various radioprotective substances have been proposed, comprehensive strategies are needed to modulate radiotoxicity. In this regard, compounds from green tea (Camellia sinensis), with antioxid [...] |
Paranitrophenol and Organic Azo Dye Degradation: Catalytic Power of Terminalia Leaf Silver NanoparticlesAbstract Terminalia species is a widely available plant that can be used to synthesise silver nanoparticles (AgNPs) and harness their catalytic capacity. This experimental design will explore the potential of Terminalia AgNPs in contributing to the degradation process of toxic chemicals generated by industries such as textiles, food, and pharmaceuticals. This [...] |
Effects of Trauma, Shame, and Self-Criticism on Hoarding: Comparative Data and Treatment ImplicationsAbstract Severe trauma has a significant impact on self-attitudes and emotions, such as self-criticism and shame, and psychological symptoms. This topic has been more well studied among populations with Trauma and Stress-Related Disorders, but examined to a lesser extent in other clinical populations where adverse life events and potentially traumatic events [...] |
Technology to Help People with Blindness and Intellectual Disability Manage Indoor Travel: Anticipating and Bypassing Obstaclesby
Giulio E. Lancioni
,
Gloria Alberti
,
Chiara Filippini
,
Nirbhay N. Singh
,
Mark F. O’Reilly
and
Jeff Sigafoos
Abstract Recent work with people with blindness and intellectual disability assessed a technology-aided program intended to help eight participants travel indoor routes to reach relevant destinations. The technology included a smartphone, two barcode readers worn by the participants at their ankles, barcodes displayed at specific points of the travel routes [...] |
From Vision to Strategy: Expanding Metaversal Integrative Healthcare with DAOs and Blockchain EcosystemsAbstract Legacy, profit-driven organizational structures often lack the adaptability, equity, and innovation required for the evolving complexities of contemporary patient-centered care. They can limit access, constrain options, impose financial burdens, and hinder optimized delivery. Here, we propose a new architecture for metaversal integrative healthcare [...] |
Differential Expression of MiR-21 and MiR-19 in Biliary Atresia: Diagnostic Potential and Therapeutic Implicationsby
Mahintaj Dara
,
Negar Azarpira
,
Nasrin Motazedian
,
Mahdokht Hossein-Aghdaie
,
Seyed-Mohsen Dehghani
,
Bita Geramizadeh
and
Elaheh Esfandiari
Abstract Biliary atresia (BA), a severe pediatric liver disease of unknown etiology, causes neonatal jaundice, progressive cholestasis, and life-threatening liver fibrosis. Emerging evidence suggests microRNAs (miRNAs) – small non-coding RNAs that regulate gene expression by binding target mRNAs may play a role in BA pathogenesis. Circulating miRNAs have shown [...] |
Risk Assessment in Clinical Histocompatibility Testing: Challenges, Strategies, and Future DirectionsAbstract Though the role of clinical histocompatibility testing is fundamental to successful transplant, systematic risk assessment and mitigation strategies remain underutilised in this domain. This review addresses risk identification, analysis, and control measures across the pre-analytical, analytical, and post-analytical phases of clinical histocompatibilit [...] |
Loneliness, Love and Their Connection: A Commentaryby
Ami Rokach
Abstract A significant social stigma is associated with loneliness. The prevalence of social isolation, in the dawn of the 21st century points to the growing isolation in America. Lonely people who commonly display negative self-perceptions, show great difficulty to establish social ties, and that may be related to their personal inadequacies, or socially undesi [...] |
Evaluation of Full Blood Count–Derived Inflammatory Indices (SII, SIRI, PIV, NLR) in Behçet’s Disease Patients and Healthy ControlsAbstract This study investigated three novel complete blood count–derived inflammatory biomarkers Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Pan-Immune-Inflammation Value (PIV) and their relationship with clinical features of Behçet’s Disease (BD). Established markers, including neutrophil-to-lymphocyte ratio [...] |
Episomal Vectors: Principle, Utility, and Applicationby
Masahiro Sato
,
Emi Inada
,
Satoshi Watanabe
,
Issei Saitoh
,
Naoko Kubota
,
Yoko Iwase
,
Kazunori Morohoshi
and
Shingo Nakamura
Abstract An episomal vector is a plasmid- or virus-based vector that is present extrachromosomally in cells after transfection. Although it disappears during cell proliferation, it can exist in non-dividing cells, such as neuronal and muscular cells, and continues to express a gene of interest (GOI). Such episomal vectors are usually based on sequences from [...] |
Opportunities, Dilemmas, and Limitations in Applying "Healthy Living" and "Aging in Place" in Designs for New Housing Concepts in Dutch NeighborhoodsAbstract This article explores the ongoing work associated with the masterclasses "Towards an Inclusive Living Environment." It critically examines the concept of healthy living for all and aging in place by studying neighborhoods within Dutch cities. The article argues that creating inclusive, healthy environments fosters well-being and promotes a lifestyle [...] |
Investigating Mental Health Literacy and Its Relationship with Addiction to Social Networks among Allied Medical Sciences StudentsAbstract The widespread use of social media among college students has become a significant concern due to its potential impact on mental health and addictive behaviors. Social media platforms, while offering numerous benefits, can also foster environments that contribute to addiction, depression, and anxiety. College students, in particular, are vulnerable [...] |
Biochemical Foundations of Emotion Regulation: Implications for Pharmacological and Psychological Interventions-A Narrative ReviewAbstract Emotion regulation (ER) involves processes by which individuals modulate the intensity, duration, and expression of emotional responses, and its dysregulation is associated with a broad spectrum of psychological disorders. While traditionally conceptualized within psychological frameworks, ER is increasingly recognized as biologically grounded, involvin [...] |
The Role of Artificial Intelligence in Microplastic Pollution Studies and ManagementAbstract Artificial intelligence (AI) is reshaping microplastic research by enabling faster, more accurate, and scalable detection, characterization, and modeling. Deep learning automates the identification and classification of microplastics from microscopy images, while machine learning accelerates the recognition of polymers from Raman and infrared spectra [...] |
Nursing Care for a Patient with a Risk of Suicide Due to Depression Using the Solution-Focused Brief Therapy Approach: Case StudyAbstract Adolescent depression is linked to suicidal ideation and attempts. Nurses are well-positioned to deliver brief, supportive interventions. Solution-Focused Brief Therapy (SFBT) emphasizes solutions and the activation of personal resources. To describe the feasibility and clinical utility of SFBT, delivered alongside pharmacotherapy, for reducing suicide [...] |
Rapid Green Synthesis of Silver Nanoparticles and Alginate-Silver Nanocomposite Beads Using Mashmoom (Ocimum basilicum), a Bahraini Household Medicinal HerbAbstract The study focuses on the rapid green synthesis of silver nanoparticles (AgNPs) and alginate-silver nanocomposite (Alg-AgNc) beads using sweet basil or Mashmoom (Ocimum basilicum), a common household medicinal herb in Bahrain. The aqueous extract of mashmoom was used as a reducing and stabilizing agent in the reduction of the precursor salt, silver nitra [...] |
Sleep and Mood as Mechanisms Linking Trauma Exposure to Alcohol Use in South African First Responders: A Serial Mediation AnalysisAbstract First responders are routinely exposed to traumatic events in the line of duty, placing them at heightened risk for adverse mental health outcomes, including substance use. This study investigated the psychological mechanisms linking trauma exposure to alcohol use, specifically examining the serial mediating roles of insomnia and depression. A sample [...] |
Cultural Cells: A Circular Economy-Driven Blueprint for Creative Tourism and Regional Revitalization in GreeceAbstract This study proposes a novel creative tourism model integrating artistic creation with circular economy principles to foster regional revitalization in North Euboea, Greece. Employing a case study approach, it develops the concept of “Cultural Cells”—dedicated hubs for artists and art students specializing in painting and sculpture—designed to [...] |
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